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dc.contributor.authorPérez de Val, Bernat
dc.contributor.authorPerea, Claudia
dc.contributor.authorEstruch, Josep
dc.contributor.authorSolano-Manrique, Carlos
dc.contributor.authorRiera, Carles
dc.contributor.authorSanz, Albert
dc.contributor.authorVidal, Enric
dc.contributor.authorVelarde, Roser
dc.contributor.otherProducció Animalca
dc.date.accessioned2022-11-07T15:35:28Z
dc.date.available2022-11-07T15:35:28Z
dc.date.issued2022-09-20
dc.identifier.citationPérez de Val, Bernat, Claudia Perea, Josep Estruch, Carlos Solano-Manrique, Carles Riera, Albert Sanz, Enric Vidal, and Roser Velarde. 2022. "Generalized Tuberculosis Due To Mycobacterium Caprae In A Red Fox Phylogenetically Related To Livestock Breakdowns". BMC Veterinary Research 18 (1). doi:10.1186/s12917-022-03454-7.ca
dc.identifier.issn1746-6148ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/1961
dc.description.abstractBackground Tuberculosis (TB) due to Mycobacterium caprae is endemic in goat herds and free-ranging wild boars in Spain, causing infections in other livestock or wild animals to a lesser extent. TB infection in foxes is infrequently reported and they are usually considered spillover hosts of TB. Case presentation A blind, depressed and severely emaciated red fox (Vulpes vulpes) was admitted to a rehabilitation center. After clinical examination it was humanely sacrificed. At necropsy, generalized TB lesions were observed that were subsequently confirmed by histopathology along with a co-infection with canine distemper virus. M. caprae was isolated from mycobacterial culture and spoligotype SB0415 was identified. Whole genome sequencing (WGS) of the isolated M. caprae was carried out and single nucleotide polymorphisms (SNP) were compared with other sequences of M. caprae isolated from livestock and wildlife of the same area throughout the last decade. Conclusions This is the first reported case of TB due to M. caprae in a fox in the Iberian Peninsula. WGS and SNP analysis, together with spatial-temporal investigations, associated this case with recent M. caprae outbreaks in cattle and goat herds of the area. The results indicated transmission of M. caprae between livestock and the fox, suggesting that this species may occasionally play a role in the epidemiology of animal TB.ca
dc.format.extent6ca
dc.language.isoengca
dc.publisherBMCca
dc.relation.ispartofBMC Veterinary Researchca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleGeneralized tuberculosis due to Mycobacterium caprae in a red fox phylogenetically related to livestock breakdownsca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.relation.projectIDEC/INTERREG-POCTEFA/EFA357-19/EU/Red de investigación y desarrollo de herramientas innovadoras para el control de la tuberculosis animal/INNOTUBca
dc.subject.udc619ca
dc.identifier.doihttps://doi.org/10.1186/s12917-022-03454-7ca
dc.contributor.groupSanitat Animalca


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