Ultraviolet Light (UV) Inactivation of Porcine Parvovirus in Liquid Plasma and Effect of UV Irradiated Spray Dried Porcine Plasma on Performance of Weaned Pigs
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Author
Polo, Javier
Rodríguez, Carmen
Ródenas, Jesús
Russell, Louis E.
Campbell, Joy M.
Crenshaw, Joe D.
Publication date
2015-07-14ISSN
1932-6203
Abstract
A novel ultraviolet light irradiation (UV-C, 254 nm) process was designed as an additional safety feature for manufacturing of spray dried porcine plasma (SDPP). In Exp. 1, three 10-L batches of bovine plasma were inoculated with 105.2±0.12 tissue culture infectious dose 50(TCID50) of porcine parvovirus (PPV) per mL of plasma and subjected to UV-C ranging from 0 to 9180 J/L. No viable PPV was detected in bovine plasma by micro-titer assay in SK6 cell culture after UV-C at 2295 J/L. In Exp. 2, porcine plasma was subjected to UV-C (3672 J/L), then spray dried and mixed in complete mash diets. Diets were a control without SDPP (Control), UV-C SDPP either at 3% (UVSDPP3) or 6% (UVSDPP6) and non-UV-C SDPP at 3% (SDPP3) or 6% (SDPP6). Diets were fed ad libitum to 320 weaned pigs (26 d of age; 16
pens/diet; 4 pigs/pen) for 14 d after weaning and a common diet was fed d 15 to 28. During d 0 to 14, pigs fed UVSDPP3, UVSDPP6, or SDPP6 had higher (P < 0.05) weight gain and feed intake than control. During d 0 to 28, pigs fed UVSDPP3 and UVSDPP6 had higher (P< 0.05) weight gain and feed intake than control and SDPP3, and SDPP6 had higher (P <0.05) feed intake than control. Also, pigs fed UVSDPP had higher (P < 0.05) weight gain than pigs fed SDPP. In conclusion, UV-C inactivated PPV in liquid plasma and UVSDPP used in pig feed had no detrimental effects on pig performance.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
12
Publisher
Public Library of Science
Is part of
PLoS ONE
Citation
Polo, Javier, Carmen Rodríguez, Jesús Ródenas, Louis E. Russell, Joy M. Campbell, Joe D. Crenshaw, David Torrallardona, and Joan Pujols. 2015. "Ultraviolet Light (UV) Inactivation Of Porcine Parvovirus In Liquid Plasma And Effect Of UV Irradiated Spray Dried Porcine Plasma On Performance Of Weaned Pigs". PLOS ONE 10 (7): e0133008. doi:10.1371/journal.pone.0133008.
Grant agreement number
CDTI/ /IDI-20080591/ES/E! 4192 SUPLHEMO. HIERRO HÉMICO CONCENTRADO BIO-ASIMILABLE/
CDTI/Programa Nacional de Proyectos de Desarrollo Experimental/IDI-20101014/ES/PLASMA ANIMAL DESHIDRATADO: MODULACIÓN DE LA RESPUESTA INFLAMATORIA MUCOSAL Y BIOSEGURIDAD/
Program
Nutrició Animal
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2510]
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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/