Genetically superior European sea bass (Dicentrarchus labrax) and nutritional innovations: Effects of functional feeds on fish immune response, disease resistance, and gut microbiota
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Author
Rimoldi, Simona
Montero, Daniel
Serradell, Antonio
Acosta, Felix
Haffray, Pierrick
Hostins, Barbara
Fontanillas, Ramon
Allal, François
Bajek, Aline
Terova, Genciana
Publication date
2023-09-21ISSN
2352-5134
Abstract
The objective of this study was to determine if selected fish genotypes could benefit from the use of functional
additives in novel aqua feed formulations to improve growth performance, gut microbiota, immune response,
and disease resistance in fish. Two batches of juvenile European sea bass selected for high growth (HG; selected
sires x selected dams), and wild types (WT; wild sires x selected females) were fed a “future diet” coated with
three different functional additives for 12 weeks as follows: (i) 2 weeks with a high dose, followed by (ii) 10
weeks with a low dose. The functional additives tested were a mixture of probiotics (PROB), organic acids (ORG),
and phytogens (PHYTO). A pathogen challenge test (Vibrio anguillarum) and a stress condition (overcrowding)
were performed after each dose. At the end of the feeding experiment, fish from the HG group performed better
than fish from the WT group in terms of body weight, relative growth, SGR, and DGI. The results of the two
challenge tests performed after two weeks of high dose and ten weeks of low dose showed a significant effect of
diet on fish survival. GALT-associated gene expression analysis revealed an interaction between the genotype and
diet for il-1β in the distal gut. Finally, regarding the gut microbiota, discriminant analysis showed no clear
separation between fish fed the future diet and those fed the same diet with experimental additives. Nevertheless,
the relative abundance of certain taxa varied between experimental groups. For example, fish fed the ORG diet
had higher relative abundance of Streptococcus in both genotypes, whereas fish fed the PHYTO diet had higher
abundance of Lactobacillales. In contrast, fish fed PROB had lower abundance of Pseudomonas and Acinetobacter.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
639 - Hunting. Fishing. Fish breeding
Pages
17
Publisher
Elsevier
Is part of
Aquaculture Reports
Citation
Rimoldi, Simona, Daniel Montero, Silvia Torrecillas, A. Serradell, F. Acosta, Pierrick Haffray, Bárbara Hostins, et al. 2023. “Genetically Superior European Sea Bass (Dicentrarchus Labrax) and Nutritional Innovations: Effects of Functional Feeds on Fish Immune Response, Disease Resistance, and Gut Microbiota.” Aquaculture Reports 33 (December): 101747. https://doi.org/10.1016/j.aqrep.2023.101747.
Grant agreement number
EC/H2020/818367/EU/Genomic and nutritional innovations for genetically superior farmed fish to improve efficiency in European aquaculture/AquaIMPACT
Program
Aqüicultura
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2555]
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