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dc.contributor.authorFranzo, Giovanni
dc.contributor.authorKekarainen, Tuija
dc.contributor.authorLlorens, Anna
dc.contributor.authorCorrea-Fiz, Florencia
dc.contributor.authorSegalés, Joaquim
dc.contributor.otherProducció Animalca
dc.date.accessioned2019-04-03T13:44:55Z
dc.date.available2019-11-09T23:01:18Z
dc.date.issued2018-11-09
dc.identifier.citationFranzo, Giovanni, Tuija Kekarainen, Anna Llorens, Florencia Correa-Fiz, and Joaquim Segalés. 2018. "Exploratory Metagenomic Analyses Of Periweaning Failure-To-Thrive Syndrome-Affected Pigs". Veterinary Record 184 (1): 25-25. BMJ. doi:10.1136/vr.105125.ca
dc.identifier.issn0042-4900ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/246
dc.description.abstractModern pig farming is characterised by the emergence of several syndromes whose aetiology is unclear or has a multifactorial origin, including periweaning failure-to-thrive syndrome (PFTS). In fact, its specific aetiology remains elusive, although several causes have been investigated over time. The present study aimed to investigate the potential role of viral agents in PFTS-affected and healthy animals by evaluating the virome composition of different organs using a metagenomic approach. This analysis allowed demonstrating a higher abundance of Porcine parvovirus 6 (PPV6) in healthy subjects while Ungulate bocaparvovirus 2 (BoPV2), Ungulate protoparvovirus 1 (PPV) and Porcine circovirus 3 (PCV-3) were increased in pigs with PFTS. No differential abundance of RNA viruses was found between PFTS-affected and control pigs. Remarkably, this is the first molecular characterisation of PPV6 and BoPV2 in Spain and one of the few all around the world, supporting their apparent widespread circulation. Interestingly, PCV-3 has been recently identified in several clinical-pathological conditions as well as in healthy pigs, while BoPV2 pathogenic potential is unknown. Although obtained results must be taken as preliminary, they open the door for further studies on the potential role of these viruses or their combination as predisposing factor/s for PFTS occurrence.ca
dc.format.extent21ca
dc.language.isoengca
dc.publisherBMJ Publishing Groupca
dc.relation.ispartofVeterinary Recordca
dc.rightsAttribution-NonCommercial 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titleExploratory metagenomic analyses of periweaning failure-to-thrive syndrome-affected pigsca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/acceptedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.identifier.doihttp://dx.doi.org/10.1136/vr.105125ca
dc.contributor.groupSanitat Animalca


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/