The haplotype-resolved T2T reference genome highlights structural variation underlying agronomic traits of melon
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Author
Li, Guoli
Tang, Lingli
He, Yunhua
Xu, Yongyang
Bendahmane, Abdelhafid
Garcia-Mas, Jordi
Lin, Tao
Zhao, Guangwei
Publication date
2023-09-04ISSN
2052-7276
Abstract
Melon (Cucumis melo L.) is an important vegetable crop that has an extensive history of cultivation. However, the genome of wild and semi-wild melon types that can be used for the analysis of agronomic traits is not yet available. Here we report a chromosome-level T2T genome assembly for 821 (C. melo ssp. agrestis var. acidulus), a semi-wild melon with two haplotypes of ~373 Mb and ~364 Mb, respectively. Comparative genome analysis discovered a significant number of structural variants (SVs) between melo (C. melo ssp. melo) and agrestis (C. melo ssp. agrestis) genomes, including a copy number variation located in the ToLCNDV resistance locus on chromosome 11. Genome-wide association studies detected a significant signal associated with climacteric ripening and identified one candidate gene CM_ac12g14720.1 (CmABA2), encoding a cytoplasmic short chain dehydrogenase/reductase, which controls the biosynthesis of abscisic acid. This study provides valuable genetic resources for future research on melon breeding.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
633 - Field crops and their production
Pages
13
Publisher
Oxford University Press
Is part of
Horticulture Research
Citation
Li, Guoli, Lingli Tang, Yue He, Yong Xu, Abdelhafid Bendahmane, Jordi García-Más, Tao Lin, and Guangwei Zhao. 2023. “The Haplotype-Resolved T2T Reference Genome Highlights Structural Variation Underlying Agronomic Traits of Melon.” Horticulture Research, September. doi:10.1093/hr/uhad182.
Program
Genòmica i Biotecnologia
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2555]