Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquito Culex pipiens
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Author
Gil, Patricia
Exbrayat, Antoni
Loire, Etienne
Rakotoarivony, Ignace
Charriat, Florian
Morel, Côme
Baldet, Thierry
Boisseau, Michel
Marie, Albane
Frances, Benoît
L’Ambert, Gregory
Bessat, Mohamed
Otify, Yehia
Goffredo, Maria
Mancini, Giuseppe
Birnberg, Lotty
Ayari, Emna
Mejri, Selma
Sghaier, Soufen
Bennouna, Amal
El Rhaffouli, Hicham
Balenghien, Thomas
Chlyeh, Ghita
Fihri, Ouafaa Fassi
Reveillaud, Julie
Simonin, Yannick
Eloit, Marc
Gutierrez, Serafin
Publication date
2023-08-24ISSN
2057-1577
Abstract
Our knowledge of the diversity of eukaryotic viruses has recently undergone a massive expansion. This diversity could infuence host
physiology through yet unknown phenomena of potential interest to the felds of health and food production. However, the assembly
processes of this diversity remain elusive in the eukaryotic viromes of terrestrial animals. This situation hinders hypothesis-driven
tests of virome infuence on host physiology. Here, we compare taxonomic diversity between different spatial scales in the eukaryotic
virome of the mosquito Culex pipiens. This mosquito is a vector of human pathogens worldwide. The experimental design involved
sampling in fve countries in Africa and Europe around the Mediterranean Sea and large mosquito numbers to ensure a thorough
exploration of virus diversity. A group of viruses was found in all countries. This core group represented a relatively large and diverse
fraction of the virome. However, certain core viruses were not shared by all host individuals in a given country, and their infection
rates fuctuated between countries and years. Moreover, the distribution of coinfections in individual mosquitoes suggested random
co-occurrence of those core viruses. Our results also suggested differences in viromes depending on geography, with viromes tending
to cluster depending on the continent. Thus, our results unveil that the overlap in taxonomic diversity can decrease with spatial scale
in the eukaryotic virome of C. pipiens. Furthermore, our results show that integrating contrasted spatial scales allows us to identify
assembly patterns in the mosquito virome. Such patterns can guide future studies of virome infuence on mosquito physiology.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
14
Publisher
Oxford University Press
Is part of
Virus Evolution
Citation
Gil, Patricia, Antoni Exbrayat, Étienne Loire, Ignace Rakotoarivony, Florian Charriat, Carlos Médicis Morel, Thierry Baldet, et al. 2023. “Spatial Scale Influences the Distribution of Viral Diversity in the Eukaryotic Virome of the Mosquito Culex Pipiens.” Virus Evolution 9 (2). https://doi.org/10.1093/ve/vead054.
Grant agreement number
EC/FP7/613996/EU/Emerging viral vector borne diseases/VMERGE
Program
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2555]
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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/