Show simple item record

dc.contributor.authorAlves, Ricardo N.
dc.contributor.authorRambla-Alegre, Maria
dc.contributor.authorBraga, Ana Catarina
dc.contributor.authorMaulvault, Ana L.
dc.contributor.authorBarbosa, Vera
dc.contributor.authorCampàs, Mònica
dc.contributor.authorReverté, Laia
dc.contributor.authorFlores, Cintia
dc.contributor.authorCaixach, Josep
dc.contributor.authorKilcoyne, Jane
dc.contributor.authorCosta, Pedro Reis
dc.contributor.authorDiogène, Jorge
dc.contributor.authorMarques, António
dc.contributor.otherProducció Animalca
dc.date.accessioned2019-05-08T13:09:24Z
dc.date.available2020-04-27T22:01:11Z
dc.date.issued2019-04-28
dc.identifier.citationAlves, Ricardo N., Maria Rambla-Alegre, Ana Catarina Braga, Ana L. Maulvault, Vera Barbosa, Mònica Campàs, and Laia Reverté et al. 2019. "Bioaccessibility Of Lipophilic And Hydrophilic Marine Biotoxins In Seafood: An In Vitro Digestion Approach". Food And Chemical Toxicology 129: 153-161. Elsevier BV. doi:10.1016/j.fct.2019.04.041.ca
dc.identifier.issn0278-6915ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/380
dc.description.abstractThis study aimed to assess the bioaccessibility of different marine biotoxins in naturally contaminated shellfish and fish gonads using an in vitro digestion methodology. In general, hydrophilic toxins (domoic acid, paralytic shellfish poisoning toxins and tetrodotoxins) showed higher bioaccessibility than lipophilic ones (okadaic acid and azaspiracids). The bioaccessibility of toxins from the okadaic acid group ranged from 69% (raw European razor clams) to 74% (raw donax clams). Regarding azaspiracids, 47% of the initial content was bioaccessible in steamed blue mussel. As for hydrophilic toxins, 100% of the initial content was bioaccessible after digestion in raw shellfish and puffer fish gonads. The total tetrodotoxin bioaccessibility in puffer fish gonads decreased significantly after steaming. The profile of tetrodotoxins changed during the digestion process: TTX and 11-norTTX-6S-ol analogues decreased significantly after digestion, but the 5,6,11-trideoxy TTX analogue increased in both raw and steamed puffer fish gonads. These preliminary findings confirm the need to consider bioaccessibility data in future seafood risk assessment, as such information enables a more accurate and realistic estimation of potential seafood hazards, particularly in what concerns lipophilic toxins, therefore, constituting a crucial tool in the refinement of regulatory limits for the presence of biotoxins in seafood.ca
dc.format.extent45ca
dc.language.isoengca
dc.publisherElsevierca
dc.relation.ispartofFood and Chemical Toxicologyca
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleBioaccessibility of lipophilic and hydrophilic marine biotoxins in seafood: An in vitro digestion approachca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/acceptedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.relation.projectIDEC/FP7/311820/EU/Priority environmental contaminants in seafood: safety assessment, impact and public perception/ECSAFESEAFOODca
dc.subject.udc63ca
dc.identifier.doihttps://doi.org/10.1016/j.fct.2019.04.041ca
dc.contributor.groupAigües Marines i Continentalsca


Files in this item

 
 

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/