Browsing PUBLICACIONS CIENTÍFIQUES by Author "Campàs, Mònica"
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A fast magnetic bead-based colorimetric immunoassay for the detection of tetrodotoxins in shellfish
Campàs, Mònica; Reverté, Jaume; Rambla-Alegre, Maria; Campbell, Katrina; Gerssen, Arjen; Diogène, Jorge (Food and Chemical Toxicology, 2020-04-05) Aigües Marines i ContinentalsTetrodotoxin (TTX) is a potent neurotoxin responsible for many food poisoning incidents and some fatalities. Although mainly associated with the consumption of pufferfish, in recent years, TTX has been ... -
A Roadmap for Hazard Monitoring and Risk Assessment of Marine Biotoxins on the Basis of Chemical and Biological Test Systems
Daneshian, Mardas; Botana, Luis M.; Bottein, Marie-Yasmine Dechraoui; Buckland, Gemma; Campàs, Mònica; Dennison, Ngaire; Dickey, Robert W.; Diogène, Jorge; Fessard, Valérie; Hartung, Thomas; Humpage, Andrew; Leist, Marcel; Molgó, Jordi; Quilliam, Michael A.; Rovida, Costanza; Suarez-Isla, Benjamin A.; Tubaro, Aurelia; Wagner, Kristina; Zoller, Otmar; Dietrich, Daniel (ALTEX - Alternatives to Animal Experimentation, 2013-11-01) Aigües Marines i ContinentalsAquatic food accounts for over 40% of global animal food products, and the potential contamination with toxins of algal origin – marine biotoxins – poses a health threat for consumers. The gold standards ... -
A Single-Tube HNB-Based Loop-Mediated Isothermal Amplification for the Robust Detection of the Ostreid herpesvirus 1
Zaczek-Moczydłowska, Maja A.; Mohamed-Smith, Letitia; Toldrà, Anna; Hooper, Chantelle; Campàs, Mònica; Furones, M.Dolors; Bean, Tim P.; Campbell, Katrina (International Journal of Molecular Sciences, 2020-09-09) Aigües Marines i Continentals; AqüiculturaThe Ostreid herpesvirus 1 species affects shellfish, contributing significantly to high economic losses during production. To counteract the threat related to mortality, there is a need for the development ... -
A smartphone-controlled amperometric immunosensor for the detection of Pacific ciguatoxins in fish
Campàs, Mònica; Leonardo, Sandra; Oshiro, Naomasa; Kuniyoshi, Kyoko; Tsumuraya, Takeshi; Hirama, Masahiro; Diogène, Jorge (Food Chemistry, 2021-12-02) Aigües Marines i ContinentalsCiguatoxins (CTXs) are marine neurotoxins produced by microalgae of the genera Gambierdiscus and Fukuyoa. CTXs may reach humans through food webs and cause ciguatera fish poisoning (CFP). An immunosensor ... -
Addressing the analytical challenges for the detection of ciguatoxins using an electrochemical biosensor
Leonardo, Sandra; Gaiani, Greta; Tsumuraya, Takeshi; Hirama, Masahiro; Turquet, Jean; Sagristà, Núria; Rambla-Alegre, Maria; Flores, Cintia; Caixach, Josep; Diogène, Jorge; O'Sullivan, Ciara K.; Alcaraz, Carles; Campàs, Mònica (Analytical Chemistry, 2020-03-05) Aigües Marines i ContinentalsThe importance of ciguatoxins (CTXs) in seafood safety and their emerging occurrence in locations far away from tropical areas highlight the need for simple and low-cost methods for the sensitive and ... -
Alternative Methods for the Detection of Emerging Marine Toxins: Biosensors, Biochemical Assays and Cell-Based Assays
Reverté, Laia; Soliño, Lucía; Carnicer, Olga; Diogène, Jorge; Campàs, Mònica (Marine Drugs, 2014-11-26) Aigües Marines i ContinentalsThe emergence of marine toxins in water and seafood may have a considerable impact on public health. Although the tendency in Europe is to consolidate, when possible, official reference methods based ... -
An Updated Review of Tetrodotoxin and Its Peculiarities
Katikou, Panagiota; Gokbulut, Cengiz; Kosker, Ali Rıza; Campàs, Mònica; Ozogul, Fatih (Marine Drugs, 2022-01-03) Aigües Marines i ContinentalsTetrodotoxin (TTX) is a crystalline, weakly basic, colorless organic substance and is one of the most potent marine toxins known. Although TTX was first isolated from pufferfish, it has been found in ... -
Assessment of cytotoxicity in ten strains of Gambierdiscus australes from Macaronesian Islands by neuro-2a cell-based assays
Reverté, Laia; Toldrà, Anna; Andree, Karl B.; Fraga, Santiago; de Falco, Giada; Campàs, Mònica; Diogène, Jorge (Journal of Applied Phycology, 2018-06-15) Aigües Marines i Continentals; AqüiculturaWithin the dinoflagellate genus Gambierdiscus several species are well-known producers of ciguatoxins (CTXs) and maitotoxins (MTXs). These compounds are potent marine toxins that accumulate through the ... -
Automated Patch Clamp for the Detection of Tetrodotoxin in Pufferfish Samples
Campàs, Mònica; Reverté, Jaume; Tudó, Àngels; Alkassar, Mounira; Diogène, Jorge; Sureda, Francesc X. (Marine Drugs, 2024-04-15) Aigües Marines i ContinentalsTetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. ... -
Bioaccessibility of lipophilic and hydrophilic marine biotoxins in seafood: An in vitro digestion approach
Alves, Ricardo N.; Rambla-Alegre, Maria; Braga, Ana Catarina; Maulvault, Ana L.; Barbosa, Vera; Campàs, Mònica; Reverté, Laia; Flores, Cintia; Caixach, Josep; Kilcoyne, Jane; Costa, Pedro Reis; Diogène, Jorge; Marques, António (Food and Chemical Toxicology, 2019-04-28) Aigües Marines i ContinentalsThis study aimed to assess the bioaccessibility of different marine biotoxins in naturally contaminated shellfish and fish gonads using an in vitro digestion methodology. In general, hydrophilic toxins ... -
Biosensors Based on Isothermal DNA Amplification for Bacterial Detection in Food Safety and Environmental Monitoring
Leonardo, Sandra; Toldrà, Anna; Campàs, Mònica (Sensors, 2021-01-16) Aigües Marines i ContinentalsThe easy and rapid spread of bacterial contamination and the risk it poses to human health makes evident the need for analytical methods alternative to conventional time-consuming laboratory-based ... -
Cell immunolocalization of ciguatoxin-like compounds in the benthic dinoflagellate Gambierdiscus australes M. Chinain & M.A. Faust by confocal microscopy
Honsell, Giorgio; Gaiani, Greta; Hirama, Masahiro; Pelin, Marco; Tubaro, Aurelia; Tsumuraya, Takeshi; Campàs, Mònica (Harmful Algae, 2022-11-23) Aigües Marines i ContinentalsDinoflagellates of the genera Gambierdiscus and Fukuyoa are able to produce potent neurotoxins like ciguatoxins (CTXs), which, after biooxidation in fish, are responsible for ciguatera intoxication. An ... -
Colorimetric DNA-based assay for the specific detection and quantification of Ostreopsis cf. ovata and Ostreopsis cf. siamensis in the marine environment
Toldrà, Anna; Alcaraz, Carles; Andree, Karl B.; Fernández-Tejedor, Margarita; Diogène, Jorge; Katakis, Ioanis; O'Sullivan, Ciara K.; Campàs, Mònica (Harmful Algae, 2019-03-16) Aigües Marines i Continentals; AqüiculturaOstreopsis is a toxic benthic dinoflagellate largely distributed worldwide in tropical and temperate areas. In the Mediterranean Sea, periodic summer blooms have been reported and have become a serious ... -
Cyclodextrin polymer clean-up method for the detection of ciguatoxins in fish with cell-based assays
Campàs, Mònica; Leonardo, Sandra; Rambla Alegre, Maria; SAGRISTA VIDAL, NURIA; Vaya, Raquel; Diogène, Jorge; Torréns, Mabel; Fragoso, Alex (Food Chemistry, 2022-09-13) Aigües Marines i ContinentalsCiguatoxins (CTXs) are marine toxins produced by microalgae of the genera Gambierdiscus and Fukuyoa, which are transferred through the food webs, reaching humans and causing a poisoning known as ciguatera. ... -
Cyclodextrin polymers as passive sampling materials for lipophilic marine toxins in Prorocentrum lima cultures and a Dinophysis sacculus bloom in the NW Mediterranean Sea
Campàs, Mònica; Rambla-Alegre, Maria; Wirén, Charlotta; Alcaraz, Carles; Rey, María; Safont, Anna; Diogène, Jorge; Torréns, Mabel; Fragoso, Alex (Chemosphere, 2021-07-09) Aigües Marines i ContinentalsCyclodextrins, cyclic oligomers that form a conical structure with an internal cavity, are proposed as new and sustainable materials for passive sampling of lipophilic marine toxins. Two applicability ... -
Detecting harmful algal blooms with isothermal molecular strategies
Toldrà, Anna; O'Sullivan, Ciara K.; Campàs, Mònica (Trends in Biotechnology, 2019-08-06) Aigües Marines i ContinentalsThe use of isothermal nucleic acid amplification strategies to detect harmful algal blooms (HABs) is in its infancy. We describe recent advances in these systems and highlight the challenges for the ... -
Detecting harmful algal blooms with nucleic acid amplification-based biotechnological tools
Toldrà, Anna; O'Sullivan, Ciara K.; Diogène, Jorge; Campàs, Mònica (Science of The Total Environment, 2020-08-10) Aigües Marines i ContinentalsHarmful algal blooms (HABs) represent a growing threat to aquatic ecosystems and humans. Effective HAB management and mitigation efforts strongly rely on the availability of timely and in-situ tools for ... -
Detection and quantification of the toxic marine microalgae Karlodinium veneficum and Karlodinium armiger using recombinase polymerase amplification and enzyme-linked oligonucleotide assay
Toldrà, Anna; Jauset-Rubio, Míriam; Andree, Karl B.; Fernández-Tejedor, Margarita; Diogène, Jorge; Katakis, Ioanis; O'Sullivan, Ciara K.; Campàs, Mònica (Analytica Chimica Acta, 2018-07-28) Aigües Marines i Continentals; AqüiculturaKarlodinium is a dinoflagellate responsible for fish-killing events worldwide. In Alfacs Bay (NW Mediterranean Sea), the presence of two Karlodinium species (K. veneficum and K. armiger) with different ... -
Detection of azaspiracids in mussels using electrochemical immunosensors for fast screening in monitoring programs
Leonardo, Sandra; Kilcoyne, Jane; Samdal, Ingunn A.; Miles, Christopher O.; O'Sullivan, Ciara K.; Diogène, Jorge; Campàs, Mònica (Sensors and Actuators B: Chemical, 2018-02-06) Aigües Marines i ContinentalsGiven the widespread occurrence of azaspiracids (AZAs), it is clearly necessary to advance in simple and low-cost methods for the rapid detection of these marine toxins in order to protect seafood ... -
Detection of Ciguatoxins and Tetrodotoxins in Seafood with Biosensors and Other Smart Bioanalytical Systems
Reverté, Jaume; Alkassar, Mounira; Diogène, Jorge; Campàs, Mònica (Foods, 2023-05-18) Aigües Marines i ContinentalsThe emergence of marine toxins such as ciguatoxins (CTXs) and tetrodotoxins (TTXs) in non-endemic regions may pose a serious food safety threat and public health concern if proper control measures are ...