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Integrative approach using liver and duodenum RNA-Seq data identifies candidate genes and pathways associated with feed efficiency in pigs
(Springer Nature, 2018-01-11)
This study aims identifying candidate genes and pathways associated with feed efficiency (FE) in pigs. Liver and duodenum transcriptomes of 37 gilts showing high and low residual feed intake (RFI) were ...
Modulatory effect of protein and carotene dietary levels on pig gut microbiota
(Nature Research, 2019-10-10)
In this study we investigated the impact of dietary protein and carotene levels on microbial functions and composition during the last month of purebred fattening Duroc pigs. Fecal microbiota was ...
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
(Springer Nature, 2018-08-28)
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its physiological similarities. The aim of this study was to describe the ...
Link-HD: a versatile framework to explore and integrate heterogeneous microbial communities
(Oxford University Press, 2019-11-18)
Motivation We present Link-HD, an approach to integrate multiple datasets. Link-HD is a generalization of ‘Structuration des Tableaux A Trois Indices de la Statistique–Analyse Conjointe de Tableaux’, a ...
Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
(Nature Research, 2018-07-20)
In this study, we used BovineSNP50 Genotyping BeadChip data to estimate the structure, putative
ancestral origin as well as to identify regions with selective sweeps that may have had an important
role ...
A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs
(Public Library of Science, 2019-10-11)
Muscle development and lipid accumulation in muscle critically affect meat quality of livestock. However, the genetic factors underlying myofiber-type specification and intramuscular fat (IMF) accumulation ...
Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese-making properties and milk composition in Montbéliarde cows
(BMC, 2019-07-01)
Background
Milk quality in dairy cattle is routinely assessed via analysis of mid-infrared (MIR) spectra; this approach can also be used to predict the milk’s cheese-making properties (CMP) and ...
SNP co-association and network analyses identify E2F3, KDM5A and BACH2 as key regulators of the bovine milk fatty acid profile
(Nature Research, 2017-12-11)
The fatty acid (FA) profle has a considerable impact on the nutritional and technological quality of milk
and dairy products. The molecular mechanism underlying the regulation of fat metabolism in ...
Integration of GWAS, pathway and network analyses reveals novel mechanistic insights into the synthesis of milk proteins in dairy cows
(Nature Research, 2018-01-12)
The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...