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Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
(Public Library of Science, 2017-05-04)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Role of AMPK signalling pathway during compensatory growth in pigs
(BioMed Central, 2018-09-17)
Background: The molecular basis of compensatory growth in monogastric animals has not yet been fully explored.
Herewith, in this study we aim to determine changes in the pig skeletal muscle transcriptome ...
Analysis of porcine adipose tissue transcriptome reveals differences in de novo fatty acid synthesis in pigs with divergent muscle fatty acid composition
(BMC, 2013-12-01)
Background: In pigs, adipose tissue is one of the principal organs involved in the regulation of lipid metabolism.
It is particularly involved in the overall fatty acid synthesis with consequences in ...
Comparative Transcriptome Profile between Iberian Pig Varieties Provides New Insights into Their Distinct Fat Deposition and Fatty Acids Content
(MDPI, 2021-02-27)
The high deposition of intramuscular fat and the content of oleic fatty acid are characteristic of the Iberian pig. These two parameters present great variability and are differentiated amongst the ...
Association between the pig genome and its gut microbiota composition
(Nature Research, 2019-06-19)
The gut microbiota has been evolving with its host along the time creating a symbiotic relationship. In this study, we assess the role of the host genome in the modulation of the microbiota composition ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...