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Experimental and field investigations of exposure, replication and transmission of SARS-CoV-2 in pigs in the Netherlands
(Taylor & Francis Open Access, 2021-12-21)
In order to assess the risk of SARS-CoV-2 infection, transmission and reservoir development in swine, we combined results of an experimental and two observational studies. First, intranasal and intratracheal ...
Identification of African Swine Fever Virus Transcription within Peripheral Blood Mononuclear Cells of Acutely Infected Pigs
(MDPI, 2021-11-22)
African swine fever virus (ASFV) has become widespread in Europe, Asia and elsewhere, thereby causing extensive economic losses. The viral genome includes nearly 200 genes, but their expression within ...
Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
(Elsevier, 2021-09-21)
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the ...
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie
(Nature Research, 2021-08-31)
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the ...
Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health
(American Association for the Advancement of Science, 2021-03-31)
Accelerated postnatal growth is a potentially modifiable risk factor for future obesity. To study how specific breast milk components contribute to early growth and obesity risk, we quantified one-carbon ...
Whole-Genome Sequencing and De Novo Assembly of 61 Staphylococcus pseudintermedius Isolates from Healthy Dogs and Dogs with Pyoderma
(American Society for Microbiology, 2021-04-22)
We have de novo assembled and polished 61 Staphylococcus pseudintermedius genome sequences with Nanopore-only long reads. Completeness was 99.25%. The average genome size was 2.70 Mbp, comprising 2,506 ...
Deletion Mutants of the Attenuated Recombinant ASF Virus, BA71ΔCD2, Show Decreased Vaccine Efficacy
(MDPI, 2021-08-25)
African swine fever (ASF) has become the major threat to the global swine industry. Lack
of available commercial vaccines complicates the implementation of global control strategies. So
far, only live ...
Porcine circovirus 3 (PCV-3) as a causal agent of disease in swine and a proposal of PCV-3 associated disease case definition
(Wiley, 2021-06-29)
Porcine circovirus 3 (PCV-3) was discovered in 2015 using next-generation sequencing (NGS) methods. Since then, the virus has been detected worldwide in pigs displaying several clinical-pathological ...
Microbiota Variation Across Life Stages of European Field-Caught Anopheles atroparvus and During Laboratory Colonization: New Insights for Malaria Research
(Frontiers Media, 2021-11-24)
The potential use of bacteria for developing novel vector control approaches has awakened new interests in the study of the microbiota associated with vector species. To set a baseline for future malaria ...
Altered Nasal Microbiota Composition Associated with Development of Polyserositis by Mycoplasma hyorhinis
(MDPI, 2021-05-14)
Fibrinous polyserositis in swine farming is a common pathological finding in nursery animals. The differential diagnosis of this finding should include Glaesserella parasuis (aetiological agent of ...