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Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins
(Nature Research, 2021-12-10)
Combining several innate immune peptides into a single recombinant antimicrobial and immunomodulatory polypeptide has been recently demonstrated. However, the versatility of the multidomain design, the ...
Using compositional mixed-effects models to evaluate responses to amino acid supplementation in milk replacers for calves
(Elsevier, 2021-04-15)
The consequences of supplementing Lys, Met, and Thr in milk replacers (MR) for calves have been widely studied, but scarce information exists about potential roles of other AA (whether essential or not). ...
Slow-Release Urea as a Sustainable Alternative to Soybean Meal in Ruminant Nutrition
(MDPI, 2021-02-25)
Three experiments were conducted to evaluate the feasibility of using a commercial slow-release urea product (SRU; Optigen®, Alltech Inc., Nicholasville, KY, USA) as a partial replacement for vegetable ...
Complete feed versus concentrate and straw fed separately: Effect of feeding method on eating and sorting behavior, rumen acidosis, and digestibility in crossbred Angus bulls fed high-concentrate diets
(Elsevier, 2021-01-06)
The aim of this study was to evaluate the effect of feeding method on eating and sorting behavior, rumen acidosis, and apparent total tract digestibility of crossbred Angus bulls fed a high-concentrate ...
Effects of Flavonoids Extracted from Citrus aurantium on Performance, Behavior, and Rumen Gene Expression in Holstein Bulls Fed with High-Concentrate Diets in Pellet Form
(MDPI, 2021-05-13)
Flavonoid supplementation may modify the behavior and rumen inflammatory response of fattening bulls, and this could be related to the concentrate presentation (mash or pellet) form. In the present ...
The Potential of Metalloproteinase-9 Administration to Accelerate Mammary Involution and Boost the Immune System at Dry-Off
(MDPI, 2021-11-30)
The dry period is decisive for the milking performance of dairy cows. The promptness of
mammary gland involution at dry-off affects not only the productivity in the next lactation, but also
the risk ...
Correlation between L-Lactate Concentrations in Beef Cattle, Obtained Using a Hand-Held Lactate Analyzer and a Lactate Assay Colorimetric Kit
(MDPI, 2021-03-25)
Lactate is a product of anaerobic glycolysis, used in animal research as an indicator of muscle fatigue. Therefore, it has been used as an indicator of cattle response to long distance transportation. ...
A prospective longitudinal study of risk factors associated with cattle lameness in southern Alberta feedlots
(Canadian Science Publishing, 2021-03-15)
The objectives of this study were to determine the incidence proportion of lameness in feedlot cattle and the associated risk factors. Lameness was studied in two southern Alberta feedlots over a 2 yr ...
Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method
(Elsevier, 2021-02-19)
Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to ...
Selecting Subpopulations of High-Quality Protein Conformers among Conformational Mixtures of Recombinant Bovine MMP-9 Solubilized from Inclusion Bodies
(MDPI, 2021-03-16)
A detailed workflow to analyze the physicochemical characteristics of mammalian matrix metalloproteinase (MMP-9) protein species obtained from protein aggregates (inclusion bodies—IBs) was followed. ...