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Foodborne Pathogens at the Livestock–Wildlife–Human Interface in Rural Western Uganda
(Springer, 2023-06-01)
Foodborne pathogens are an important cause of morbidity and mortality worldwide. To assess the presence of Salmonella, Campylobacter and Arcobacter spp. in livestock, wildlife, and humans from different ...
Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates
(Cell Press, 2023-06-28)
SARS-CoV-2 emerged in December 2019 and quickly spread worldwide, continuously striking with an unpredictable evolution. Despite the success in vaccine production and mass vaccination programs, the ...
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections
(Cell Press, 2023-02-14)
The contribution of cross-presenting XCR1+ dendritic cells (DCs) and SIRPα+ DCs in maintaining T cell function during exhaustion and immunotherapeutic interventions of chronic infections remains poorly ...
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
(MDPI, 2023-12-27)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and
non-S INDEL ...
The PHH-1V HIPRA vaccine: a new tool in the vaccination strategy against COVID-19
(Sociedad Española de Quimioterapia, 2023-06-12)
Objectives. Vaccination against SARS-CoV-2 is essential
to mitigate the personal, social and global impact of the coronavirus disease (COVID-19) as we move from a pandemic to
an endemic phase. Vaccines ...
The economic impact of endemic respiratory disease in pigs and related interventions - a systematic review
(BMC, 2023-10-17)
Background Understanding the financial consequences of endemically prevalent pathogens within the porcine
respiratory disease complex (PRDC) and the effects of interventions assists decision-making ...
Immune responses following neonatal vaccination with conserved F4 fragment of VtaA proteins from virulent Glaesserella parasuis adjuvanted with CAF®01 or CDA
(Elsevier, 2023-06-10)
Glaesserella parasuis is a Gram-negative bacterium that colonizes the upper airways of swine, capable of causing a systemic infection called Glässer’s disease. This disease is more frequent in young ...
Experimental Inoculation of Porcine Circovirus 3 (PCV-3) in Pregnant Gilts Causes PCV-3-Associated Lesions in Newborn Piglets that Persist until Weaning
(Wiley, 2023-10-20)
Porcine circovirus 3 (PCV-3) has been detected in cases of reproductive failure but the pathogenesis of such infection is poorly
understood. So far, experimental PCV-3 inoculations have been performed ...
Quantification of camelid cytokine mRNA expression in PBMCs by microfluidic qPCR technology
(Elsevier, 2023-09-17)
Camelids are economically and socially important in several parts of the world and might carry pathogens with
epizootic or zoonotic potential. However, biological research in these species is limited ...
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation
(Springer Nature, 2023-12-18)
Acute infection and chronic infection are the two most common fates of pathogenic virus infections. While several factors that
contribute to these fates are described, the critical control points and ...