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A single, episodic event of unilateral/bilateral scrotal swelling in a group of adult boars at an Austrian boar stud
(BMC, 2023-07-14)
Background
Scrotal swelling is a clinical situation which can be caused by different aetiologies. In this case report, we describe a multi-week episode of unilateral and bilateral scrotal swelling in ...
Vaccination against swine influenza in pigs causes different drift evolutionary patterns upon swine influenza virus experimental infection and reduces the likelihood of genomic reassortments
(Frontiers Media, 2023-03-13)
Influenza A viruses (IAVs) can infect a wide variety of bird and mammal species. Their genome is characterized by 8 RNA single stranded segments. The low proofreading activity of their polymerases and ...
Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
(Cell Press, 2023-02-02)
Current COVID-19 vaccines have been associated with a decline in infection rates,
prevention of severe disease, and a decrease in mortality rates. However, SARSCoV-2 variants are continuously evolving, ...
Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies
(Elsevier, 2023-04-21)
The widespread outbreak of the monkeypox virus (MPXV) recognized in 2022 poses new challenges for public healthcare systems worldwide. With more than 86,000 people infected, there is concern that MPXV ...
Mycobacterium manresensis induces trained immunity in vitro
(Cell Press, 2023-05-13)
The COVID-19 pandemic posed a global health crisis, with new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants weakening vaccine-driven protection. Trained immunity could help tackle ...
Feeding Spray-Dried Porcine Plasma to Pigs Improves the Protection Afforded by the African Swine Fever Virus (ASFV) BA71∆CD2 Vaccine Prototype against Experimental Challenge with the Pandemic ASFV—Study 2
(MDPI, 2023-04-10)
This study aimed to evaluate the effects of feeding spray-dried porcine plasma (SDPP) on the protection afforded by the BA71∆CD2 African swine fever virus (ASFV) vaccine prototype. Two groups of pigs ...
Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs
(Frontiers Media, 2023-06-14)
Middle East respiratory syndrome coronavirus (MERS-CoV) infection can cause fatal pulmonary inflammatory disease in humans. Contrarily, camelids and bats are the main reservoir hosts, tolerant for ...
β-Cyclodextrins as affordable antivirals to treat coronavirus infection
(Elsevier, 2023-06-08)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. ...
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
(Centers for Disease Control and Prevention, 2023-02-07)
Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended ...
Annual short-burst mass anthelmintic administration reduces tuberculosis severity but not prevalence in a wildlife reservoir
(Frontiers Media, 2023-10-23)
Tuberculosis (TB), caused by the Mycobacterium tuberculosis
complex (MTC), is an important disease in both human and animal systems.
Helminths are commonly found in coinfection with MTC and TB is ...