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Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
(Elsevier, 2021-09-21)
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the ...
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
(Centers for Disease Control and Prevention, 2023-02-07)
Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended ...
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie
(Nature Research, 2021-08-31)
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the ...
Retrospective study on transmissible viral proventriculitis and chicken proventricular necrosis virus (CPNV) in the UK
(Taylor & Francis, 2019-10-21)
Chicken proventricular necrosis virus (CPNV) is a recently described birnavirus, which has been proposed to be the cause of transmissible viral proventriculitis (TVP). The understanding of the epidemiology ...
Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health
(American Association for the Advancement of Science, 2021-03-31)
Accelerated postnatal growth is a potentially modifiable risk factor for future obesity. To study how specific breast milk components contribute to early growth and obesity risk, we quantified one-carbon ...
Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status
(BMC, 2024-01-16)
Background Porcine circovirus 2 (PCV‑2) poses a signifcant economic threat for the swine industry, causing a range
of diseases collectively referred to as porcine circovirus diseases (PCVDs). Despite ...
Experimental study of the susceptibility of a European Aedes albopictus strain to dengue virus under a simulated Mediterranean temperature regime
(Wiley, 2018-07-27)
Dengue virus (DENV) has re‐emerged in Europe driven by the geographic expansion of the mosquito species Aedes albopictus and Aedes aegypti (Diptera: Culicidae) and the introduction of the virus by ...
Gut‑associated microbes are present and active in the pig nasal cavity
(Nature Research, 2024-04-11)
The nasal microbiota is a key contributor to animal health, and characterizing the nasal microbiota
composition is an important step towards elucidating the role of its diferent members. Eforts ...
A proof‑of‑concept study to investigate the efficacy of heat‑inactivated autovaccines in Mycobacterium caprae experimentally challenged goats
(Nature Research, 2022-12-22)
This study aimed to assess the efficacy of a heat-inactivated Mycobacterium caprae (HIMC) vaccine in goats experimentally challenged with the same strain of M. caprae. Twenty-one goats were divided into ...
Efficacy of parenteral vaccination against tuberculosis with heat-inactivated Mycobacterium bovis in experimentally challenged goats
(Public Library of Science, 2018-05-09)
Tuberculosis (TB) in animals is a re-emerging disease with a wide range of hosts that
causes large economic losses in livestock. Goats are particularly susceptible to TB and, in
endemic areas, vaccination ...