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Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant
(Frontiers Media, 2023-12-04)
Most COVID-19 vaccines are based on the SARS-CoV-2 Spike glycoprotein (S) or
their subunits. However, S shows some structural instability that limits its
immunogenicity and production, hampering the ...
Exploratory field study on the effects of porcine circovirus 2 (PCV-2) sow vaccination at different physiological stages mimicking blanket vaccination
(BMC, 2021-04-26)
Background: The objective of the present study was to explore the benefits of Porcine circovirus 2 (PCV-2) blanket vaccination in a sow herd on productive parameters, PCV-2 infection and immune status ...
Stable neutralizing antibody levels 6 months after mild and severe COVID-19 episodes
(Elsevier, 2021-01-31)
Background. Understanding mid-term kinetics of immunity to SARS-CoV-2 is the cornerstone for public health control of the pandemic and vaccine development. However, current evidence is rather based on ...
First identification and characterization of ovine gammaherpesvirus type 2 in horses and artiodactyla from an outbreak of malignant catarrhal fever in Mexico
(Public Library of Science, 2023-09-01)
Ovine gammaherpesvirus 2 (OvHV-2), a member of the genus Macavirus, causes sheepassociated malignant catarrhal fever (SA-MCF), a fatal lymphoproliferative disease affecting
a wide variety of ungulates ...
Transmission of severe acute respiratory syndrome coronavirus 2 from humans to animals: is there a risk of novel reservoirs?
(Elsevier, 2023-10-02)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) is a zoonotic virus able to infect humans and multiple
nonhuman animal species. Most natural infections in
companion, captive zoo, ...
Infection dynamics of porcine circovirus type 3 in longitudinally sampled pigs from four Spanish farms
(BMJ Publishing Group, 2019-04-30)
Porcine circovirus type 3 (PCV-3) is a recently discovered virus in domestic pigs and wild boar. The virus has been described in pigs with different clinical/pathological presentations and healthy ...
A shift in Porcine circovirus 3 (PCV‐3) history paradigm: Phylodynamic analyses reveal an ancient origin and prolonged undetected circulation in the worldwide swine population
(Wiley Open Access, 2019-09-30)
The identification of a new circovirus (Porcine circovirus 3, PCV-3) has raised a remarkable concern because of some analogies with Porcine circovirus 2 (PCV-2). Preliminary results suggest an extremely ...
Porcine circovirus type 3: a threat to the pig industry?
(BMJ Publishing Group, 2018-01-19)
The recent discovery of porcine circovirus 3 (PCV3) has caused some concern among field veterinarians and brought the attention of the scientific world, likely because of some similarities with porcine ...