Cerca
Ara mostrant els elements 11-20 de 35
Generalized tuberculosis due to Mycobacterium caprae in a red fox phylogenetically related to livestock breakdowns
(BMC, 2022-09-20)
Background
Tuberculosis (TB) due to Mycobacterium caprae is endemic in goat herds and free-ranging wild boars in Spain, causing infections in other livestock or wild animals to a lesser extent. TB ...
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie
(Nature Research, 2021-08-31)
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the ...
DNA vaccine based on conserved HA-peptides induces strong immune response and rapidly clears influenza virus infection from vaccinated pigs
(Public Library of Science, 2019-09-25)
Swine influenza virus (SIVs) infections cause a significant economic impact to the pork industry.
Moreover, pigs may act as mixing vessel favoring genome reassortment of diverse influenza
viruses. ...
Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats: endobronchial inoculation vs. intranasal nebulization
(Frontiers Media, 2023-08-11)
Background: Goats are natural hosts of tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats ...
Immunogenicity and protection against Mycobacterium caprae challenge in goats vaccinated with BCG and revaccinated after one year
(MDPI, 2020-12-10)
Vaccination has been proposed as a supplementary tool for the control of tuberculosis in livestock. The long-term immunogenicity elicited by bacillus Calmette-Guerin (BCG) and the efficacy of revaccination ...
A proof‑of‑concept study to investigate the efficacy of heat‑inactivated autovaccines in Mycobacterium caprae experimentally challenged goats
(Nature Research, 2022-12-22)
This study aimed to assess the efficacy of a heat-inactivated Mycobacterium caprae (HIMC) vaccine in goats experimentally challenged with the same strain of M. caprae. Twenty-one goats were divided into ...
A Rift Valley fever virus Gn ectodomain-based DNA vaccine induces a partial protection not improved by APC targeting
(Nature Research, 2018-04-20)
Rift Valley fever virus, a phlebovirus endemic in Africa, causes serious diseases in ruminants and humans. Due to the high probability of new outbreaks and spread to other continents where competent ...
Porcine Forebrain Vacuolization Associated with Wasting in Pigs: A Novel Pathological Outcome Associated with Vitamin–Mineral Deficiency?
(MDPI, 2023-07-10)
The term wasting refers to a clinical sign used to describe a physical condition characterized
by growth retardation, usually of multifactorial origin. The objective of the present study was to
describe ...
Systems analysis reveals complex biological processes during virus infection fate decisions
(Cold Spring Harbor Laboratory Press, 2019-05-28)
The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus-immune system interaction with either an efficient effector response and virus elimination or an ...
Cross-protection against African swine fever virus upon intranasal vaccination is associated with an adaptive-innate immune crosstalk
(Public Library of Science, 2022-11-09)
African swine fever virus (ASFV) is causing a worldwide pandemic affecting the porcine industry and leading to important global economic consequences. The virus causes a highly lethal hemorrhagic disease ...