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Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(BMC, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome
(Elsevier, 2020-08-15)
The microbiome plays a key role in homeostasis and health and it has been also linked to fertility and semen quality in several animal species including swine. Despite the more than likely importance ...
Link-HD: a versatile framework to explore and integrate heterogeneous microbial communities
(Oxford University Press, 2019-11-18)
Motivation We present Link-HD, an approach to integrate multiple datasets. Link-HD is a generalization of ‘Structuration des Tableaux A Trois Indices de la Statistique–Analyse Conjointe de Tableaux’, a ...
Whole-genome sequencing reveals insights into the adaptation of French Charolais cattle to Cuban tropical conditions
(BMC, 2021-01-04)
Background: In the early 20th century, Cuban farmers imported Charolais cattle (CHFR) directly from France. These
animals are now known as Chacuba (CHCU) and have become adapted to the rough environmental ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
The Identification of Runs of Homozygosity Gives a Focus on the Genetic Diversity and Adaptation of the “Charolais de Cuba” Cattle
(MDPI, 2020-11-27)
Inbreeding and effective population size (Ne) are fundamental indicators for the management and conservation of genetic diversity in populations. Genomic inbreeding gives accurate estimates of inbreeding, ...
Opportunities and limits of combining microbiome and genome data for complex trait prediction
(BMC, 2021-08-06)
Background
Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine
(BMC, 2020-12-08)
Background
Genetic pressure in animal breeding is sparking the interest of breeders for selecting elite boars with higher sperm quality to optimize ejaculate doses and fertility rates. However, the ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...