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Abrogation of the RNase activity of Erns in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs
(Taylor & Francis Open Access, 2021-08-02)
The prevalence of low virulence classical swine fever virus (CSFV) strains makes viral eradication difficult in endemic countries. However, the determinants for natural CSFV attenuation and persistence ...
Low CD4/CD8 ratio in classical swine fever postnatalpersistent infection generated at 3 weeks after birth
(Wiley, 2018-11-20)
Classical swine fever virus (CSFV) is one of the most important pathogens affectingswine. After infection with a moderate virulence strain at 8 hours after birth, CSFV isable to induce viral persistence. ...
Revisiting the genetic diversity of classical swine fever virus: A proposal for new genotyping and subgenotyping schemes of classification
(Wiley, 2018-05-25)
Classical swine fever (CSF) is a highly contagious febrile viral disease caused by CSF virus (CSFV), and it is considered one of the most important infectious diseases that affect domestic pigs and wild ...
Genetic diversification patterns in swine influenza A virus (H1N2) in vaccinated and nonvaccinated animals
(Frontiers Media, 2023-09-15)
Influenza A viruses (IAVs) are characterized by having a segmented genome, low
proofreading polymerases, and a wide host range. Consequently, IAVs are
constantly evolving in nature causing a threat ...
Identification of an Immunosuppressive Cell Population during Classical Swine Fever Virus Infection and Its Role in Viral Persistence in the Host
(MDPI, 2019-09-04)
Classical swine fever virus (CSFV) remains a highly important pathogen, causing major
losses in the swine industry. Persistent infection is highly relevant for CSFV maintenance in the field;
however, ...
Classical swine fever virus: the past, present and future
(Elsevier, 2020-09-06)
Classical swine fever (CSF) is among the most relevant viral epizootic diseases of swine. Due to its severe economic impact, CSF is notifiable to the world organisation for animal health. Strict control ...
Evolutionary-Related High- and Low-Virulent Classical Swine Fever Virus Isolates Reveal Viral Determinants of Virulence
(MDPI, 2024-01-19)
Classical swine fever (CSF) has been eradicated from Western and Central Europe but
remains endemic in parts of Central and South America, Asia, and the Caribbean. CSF virus
(CSFV) has been endemic ...
Peptide-Based Vaccines: Foot-and-Mouth Disease Virus, a Paradigm in Animal Health
(MDPI, 2021-05-08)
Vaccines are considered one of the greatest global health achievements, improving the welfare of society by saving lives and substantially reducing the burden of infectious diseases. However, few vaccines ...
Identification and Characterization of Swine Influenza Virus H1N1 Variants Generated in Vaccinated and Nonvaccinated, Challenged Pigs
(MDPI, 2021-10-16)
Influenza viruses represent a continuous threat to both animal and human health. The 2009 H1N1 A influenza pandemic highlighted the importance of a swine host in the adaptation of influenza viruses to ...
Development of a new loop-mediated isothermal amplification test for the sensitive, rapid, and economic detection of different genotypes of Classical swine fever virus
(Frontiers Media, 2024-04-15)
Background: Classical swine fever virus (CSFV) remains one of the most
important pathogens in animal health. Pathogen detection relies on viral RNA
extraction followed by RT-qPCR. Novel technologies ...