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Heterogeneous Infectivity and Pathogenesis of SARS-CoV-2 Variants Beta, Delta and Omicron in Transgenic K18-hACE2 and Wildtype Mice
(Frontiers Media, 2022-05-04)
The emerging SARS-CoV-2 variants of concern (VOCs) may display enhanced transmissibility, more severity and/or immune evasion; however, the pathogenesis of these new VOCs in experimental SARS-CoV-2 ...
Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection
(Cell Press, 2022-01-24)
To understand the determinants of long-term immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the concurrent impact of vaccination and emerging variants, we follow a ...
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
(MDPI, 2023-12-27)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and
non-S INDEL ...
Acclimation strategies in gilts to control Mycoplasma hyopneumoniae infection
(Elsevier, 2018-04-04)
This paper discusses what can be expected with regard to efficacy of antibacterial vaccines used in swine, based on the present knowledge of pathogen–host interactions. First, vaccination against bacteria ...
Histopathological and virological findings in emaciated pigs from Mexico: an exploratory study
(University of Veterinary and Pharmaceutical Sciences, Brno, 2018-06-27)
The objective of this work was to detect the presence of three main pig respiratory viral agents
(porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and
respiratory ...
Advances and gaps in SARS-CoV-2 infection models
(Public Library of Science, 2022-01-13)
AU The:global Pleaseco response nfirmthata tollhe Coronavirus adinglevelsa Disease rerepres 2019 entedcor (COVID-19) rectly: is now facing new challenges such as vaccine inequity and the emergence of ...
Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4
(Nature Research, 2018-06-27)
Middle East respiratory syndrome (MERS) represents an important respiratory disease accompanied by lethal outcome in one-third of human patients. Recent data indicate that dromedaries represent an ...
Genotyping Porcine Circovirus 3 (PCV-3) Nowadays: Does It Make Sense?
(MDPI, 2020-02-28)
The discovery of a globally distributed porcine circovirus (Porcine circovirus 3; PCV-3) has led to intense research activity and the production of a large amount of molecular data. Different research ...
The economic impact of endemic respiratory disease in pigs and related interventions - a systematic review
(BMC, 2023-10-17)
Background Understanding the financial consequences of endemically prevalent pathogens within the porcine
respiratory disease complex (PRDC) and the effects of interventions assists decision-making ...