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Now showing items 41-47 of 47
Stable neutralizing antibody levels 6 months after mild and severe COVID-19 episodes
(Elsevier, 2021-01-31)
Background. Understanding mid-term kinetics of immunity to SARS-CoV-2 is the cornerstone for public health control of the pandemic and vaccine development. However, current evidence is rather based on ...
Animal models to study the neurological manifestations of the post-COVID-19 condition
(Nature Research, 2023-08-24)
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have experienced
persistent or relapsing multi-systemic symptoms months after the onset of coronavirus ...
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity
(Nature Research, 2024-02-05)
Here we report the characterization of 17T2, a SARS-CoV-2 pan-neutralizing
human monoclonal antibody isolated from a COVID-19 convalescent individual infected during the first pandemic wave. 17T2 is a ...
Middle East respiratory coronavirus (MERS-CoV) internalized by llama alveolar macrophages does not result in virus replication or induction of pro-inflammatory cytokines
(Elsevier, 2024-03)
Severe Middle East respiratory syndrome (MERS) is characterized by massive infiltration of immune cells
in lungs. MERS-coronavirus (MERS-CoV) replicates in vitro in human macrophages, inducing high ...
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models
(Nature Research, 2024-02-27)
AgeisassociatedwithreducedefficacyofvaccinesandlinkedtohigherriskofsevereCOVID-19.Herewe
determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike
glycoprotein ...
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection
(Nature Research, 2024-03-21)
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) vaccines are crucial to fight against the coronavirus disease 2019
pandemic. Most vaccines are based on a mutated version ...
Protective effect of a polyvalent influenza DNA vaccine in pigs
(Elsevier, 2017-11-23)
Background: Influenza A virus in swine herds represents a major problem for the swine industry and poses a
constant threat for the emergence of novel pandemic viruses and the development of more effective ...