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Classical swine fever virus: the past, present and future
(Elsevier, 2020-09-06)
Classical swine fever (CSF) is among the most relevant viral epizootic diseases of swine. Due to its severe economic impact, CSF is notifiable to the world organisation for animal health. Strict control ...
Evolutionary-Related High- and Low-Virulent Classical Swine Fever Virus Isolates Reveal Viral Determinants of Virulence
(MDPI, 2024-01-19)
Classical swine fever (CSF) has been eradicated from Western and Central Europe but
remains endemic in parts of Central and South America, Asia, and the Caribbean. CSF virus
(CSFV) has been endemic ...
Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen
(Frontiers Media, 2021-03-25)
There is an urgent need to identify therapeutics for the treatment of Coronavirus disease 2019 (COVID-19). Although different antivirals are given for the clinical management of SARS-CoV-2 infection, ...
Neuropathogenesis of a highly pathogenic avian influenza virus (H7N1) in experimentally infected chickens
(BMC, 2011-10-07)
In order to understand the mechanism of neuroinvasion of a highly pathogenic avian influenza virus (HPAIV) into
the central nervous system (CNS) of chickens, specific pathogen free chickens were ...
Identification of an Immunosuppressive Cell Population during Classical Swine Fever Virus Infection and Its Role in Viral Persistence in the Host
(MDPI, 2019-09-04)
Classical swine fever virus (CSFV) remains a highly important pathogen, causing major
losses in the swine industry. Persistent infection is highly relevant for CSFV maintenance in the field;
however, ...
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection
(Frontiers Media, 2023-01-17)
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the major swine pathogens causing reproductive failure in sows. Although modified-live virus (MLV) vaccines are available, ...
Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age
(Elsevier, 2022-11-21)
Colostrum consumption is crucial for passive immunization and development of the newborn calf. However, the incidence on failed transfer of passive immunity in male calves destined to dairy-beef production ...
Computational Analysis of African Swine Fever Virus Protein Space for the Design of an Epitope-Based Vaccine Ensemble
(MDPI, 2020-12-21)
African swine fever virus is the etiological agent of African swine fever, a transmissible severe hemorrhagic disease that affects pigs, causing massive economic losses. There is neither a treatment nor ...
Evaluation of ultraviolet‐C and spray‐drying processes as two independent inactivation steps on enterotoxigenic Escherichia coli K88 and K99 strains inoculated in fresh unconcentrated porcine plasma
(Wiley, 2018-08-28)
The objectives of this study were to assess the effectiveness of an ultraviolet (UV‐C, 254 nm) irradiation system and the spray‐drying method as two independent safety steps on inactivation of Escherichia ...
Lack of detection of Mycobacterium microti infection in wild rodents from a free‑ranging wild boar outbreak area
(Springer, 2023-10-18)
Wild small rodents are considered the natural reservoirs of Mycobacterium microti, a member of the Mycobacterium tuberculosis complex (MTBC) that can cause tuberculosis (TB) in humans and animals, as ...