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Unraveling the antiviral activity of plitidepsin against SARS-CoV-2 by subcellular and morphological analysis
(Elsevier, 2022-02-26)
The pandemic caused by the new coronavirus SARS-CoV-2 has made evident the need for broad-spectrum, efficient antiviral treatments to combat emerging and re-emerging viruses. Plitidepsin is an antitumor ...
Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
(Cell Press, 2023-02-02)
Current COVID-19 vaccines have been associated with a decline in infection rates,
prevention of severe disease, and a decrease in mortality rates. However, SARSCoV-2 variants are continuously evolving, ...
Animal models to study the neurological manifestations of the post-COVID-19 condition
(Nature Research, 2023-08-24)
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have experienced
persistent or relapsing multi-systemic symptoms months after the onset of coronavirus ...
Viral and bacterial investigations on the aetiology of recurrent pig neonatal diarrhoea cases in Spain
(BioMed Central, 2018-04-05)
Neonatal diarrhoea represents a major disease problem in the early stages of animal production, increasing significantly pre-weaning mortality and piglets weaned below the target weight. Enteric diseases ...
Detection and genotyping of Porcine circovirus 2 (PCV‐2) and detection of Porcine circovirus 3 (PCV‐3) in sera from fattening pigs of different European countries
(Wiley, 2020-05-01)
PCV-2 is considered one of the most economically important viral agents in swine worldwide. Recently, PCV-3 has been found in pigs affected by different disorders and in healthy animals. The objective ...
SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity
(Nature Research, 2021-01-28)
The protective effect of neutralizing antibodies in SARS-CoV-2 infected individuals is not yet well defined. To address this issue, we have analyzed the kinetics of neutralizing antibody responses and ...
A case of uterine inclusion cysts in a sow
(BMC, 2021-11-01)
Background: Serosal inclusion cysts are thin walled-structures located on the peritoneal surface of the uterus, frequently observed as multiple cystic structures in aggregates or grape-like clusters ...
Comprehensive Analysis of Codon Usage Patterns in Chinese Porcine Circoviruses Based on Their Major Protein-Coding Sequences
(MDPI, 2022-01-03)
Porcine circoviruses (PCVs) are distributed in swine herds worldwide and represent a threat to the health of domestic pigs and the profits of the swine industry. Currently, four PCV species, including ...
Porcine Circovirus 2 Genotypes, Immunity and Vaccines: Multiple Genotypes but One Single Serotype
(MDPI, 2020-12-14)
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be considered an emerging virus anymore. Nevertheless, many aspects of its biology and epidemiology are still ...
Critical Presentation of a Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection: A Case Report
(Oxford University Press, 2021-06-23)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfections have been reported; however, most cases are milder than the primary infection. We report the first case of a ...