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On the holobiont ‘predictome’ of immunocompetence in pigs
(BMC, 2023-05-01)
Background
Gut microbial composition plays an important role in numerous traits, including immune response. Integration of host genomic information with microbiome data is a natural step in the prediction ...
Functional and association studies on the pig HMGCR gene, a cholesterol-synthesis limiting enzyme
(Cambridge University Press, 2009-10-23)
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is the rate-limiting enzyme in the biosynthesis of cholesterol. We have
studied the role of the HMGCR gene in pig lipid metabolism by means of ...
Social network analysis of agonistic behaviour and its association with economically important traits in pigs
(MDPI, 2020-11-16)
Aggression behaviour has several negative consequences on the performance and welfare of pigs. Here, the Social Network Analysis (SNA) approach was employed to (1) identify individual traits that describe ...
Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver
(Frontiers Media, 2023-09-14)
C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Role of AMPK signalling pathway during compensatory growth in pigs
(BioMed Central, 2018-09-17)
Background: The molecular basis of compensatory growth in monogastric animals has not yet been fully explored.
Herewith, in this study we aim to determine changes in the pig skeletal muscle transcriptome ...
Segregation of Regulatory Polymorphisms with Effects on the Gluteus Medius Transcriptome in a Purebred Pig Population
(Public Library of Science, 2012-04-24)
Background: The main goal of the present study was to analyse the genetic architecture of mRNA expression in muscle, a
tissue with an outmost economic importance for pig breeders. Previous studies have ...
An association analysis between a polymorphism in the SEC24A gene and lipid traits recorded in Duroc pigs
(Taylor & Francis Open Access, 2021-10-05)
By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that ...
Muscle transcriptomic profiles in pigs with divergent phenotypes for fatness traits
(BMC, 2010-06-11)
Background: Selection for increasing intramuscular fat content would definitively improve the palatability and
juiciness of pig meat as well as the sensorial and organoleptic properties of cured products. ...
A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants
(BMC, 2014-09-04)
Background: The genetic determinism of blood lipid concentrations, the main risk factor for atherosclerosis, is practically unknown in species other than human and mouse. Even in model organisms, little ...