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Impact of Cryopreservation on Viability, Phenotype, and Functionality of Porcine PBMC
(Frontiers Media, 2021-11-29)
The use of frozen peripheral blood mononuclear cells (PBMC) is common in immunological studies. The impact of freezing PBMC has been assessed using human and mice cells, but little information is available ...
Swine Dendritic Cell Response to Porcine Reproductive and Respiratory Syndrome Virus: An Update
(Frontiers Media, 2021-07-28)
Dendritic cells (DCs) are the most potent antigen-presenting cells, unique to initiate and coordinate the adaptive immune response. In pigs, conventional DCs (cDCs), plasmacytoid DCs (pDCs), and ...
The use of a whole inactivated PRRS virus vaccine administered in sows and impact on maternally derived immunity and timing of PRRS virus infection in piglets
(Wiley, 2022-04-05)
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) vaccination is usually based on administering periodically PRRS modified live virus (MLV) in sows throughout their life. Using ...
Development of pig conventional dendritic cells from bone marrow hematopoietic cells in vitro
(Frontiers Media, 2020-10-08)
In recent years, porcine dendritic cells (DCs) have been identified from pig tissues. However, studying the interaction of porcine DCs with pathogens is still difficult due to the scarcity of DCs in ...
Diversity of respiratory viruses present in nasal swabs under influenza suspicion in respiratory disease cases of weaned pigs
(Frontiers Media, 2022-10-19)
Respiratory diseases in weaned pigs are a common problem, with a complex etiology involving both viruses and bacteria. In the present study, we investigated the presence of eleven viruses in nasal swabs, ...
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection
(Frontiers Media, 2023-01-17)
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the major swine pathogens causing reproductive failure in sows. Although modified-live virus (MLV) vaccines are available, ...
Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells
(Frontiers Media, 2021-06-02)
The present study delineates the interaction of a typical PRRSV1.1 isolate 3267 (moderate virulence) with in vitro derived pig conventional dendritic cells, cDC1, cDC2, and a CD14+ population (designated ...