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Opportunities and limits of combining microbiome and genome data for complex trait prediction
(BMC, 2021-08-06)
Background
Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how ...
Overexpression of thioredoxin m in chloroplasts alters carbon and nitrogen partitioning in tobacco
(Oxford University Press, 2021-05-08)
In plants, there is a complex interaction between carbon (C) and nitrogen (N) metabolism, and its coordination is fundamental for plant growth and development. Here, we studied the influence of thioredoxin ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Cytochrome c Deficiency Differentially Affects the In Vivo Mitochondrial Electron Partitioning and Primary Metabolism Depending on the Photoperiod
(MDPI, 2021-02-26)
Plant respiration provides metabolic flexibility under changing environmental conditions by modulating the activity of the nonphosphorylating alternative pathways from the mitochondrial electron transport ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...