• Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs 

      Ramayo-Caldas, Yuliaxis; Crespo-Piazuelo, Daniel; Morata, Jordi; González-Rodríguez, Olga; Sebastià, Cristina; Castello, Anna; Dalmau, Antoni; Ramos-Onsins, Sebastian; Alexiou, Konstantinos G.; Folch, Josep M.; Quintanilla, Raquel; Ballester, Maria (Microbiology Spectrum, 2023-05-31) Benestar Animal; Genètica i Millora Animal; Genòmica i Biotecnologia
      Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...
    • Epigenetic regulation of the ELOVL6 gene is associated with a major QTL effect on fatty acid composition in pigs 

      Corominas, Jordi; Marchesi, Jorge AP; Puig-Oliveras, Anna; Revilla, Manuel; Estellé, Jordi; Alves, Estefânia; Folch, Josep M.; Ballester Devis, Maria (Genetics Selection Evolution, 2015-03-25) Genètica i Millora Animal
      Background: In previous studies on an Iberian x Landrace cross, we have provided evidence that supported the porcine ELOVL6 gene as the major causative gene of the QTL on pig chromosome 8 for palmitic ...
    • Genetic architecture of innate and adaptive immune cells in pigs 

      Ballester Devis, Maria; Jové Juncà, Teodor; Pascual, Afra; López-Serrano, Sergi; Crespo-Piazuelo, Daniel; Hernández-Banqué, Carles; González-Rodríguez, Olga; Ramayo-Caldas, Yuliaxis; Quintanilla, Raquel (Frontiers in Immunology, 2023-02-06) Genètica i Millora Animal
      Pig industry is facing new challenges that make necessary to reorient breeding programs to produce more robust and resilient pig populations. The aim of the present work was to study the genetic determinism ...
    • Genome data from a sixteenth century pig illuminate modern breed relationships 

      Ramírez, O.; Burgos-Paz, W.; Casas, E.; Ballester Devis, Maria; Bianco, E.; Olalde, I.; Santpere, G.; Novella, V.; Gut, M.; Lalueza-Fox, C.; Saña, M.; Pérez-Enciso, M. (Heredity, 2014-09-10) Genètica i Millora Animal
      Ancient DNA (aDNA) provides direct evidence of historical events that have modeled the genome of modern individuals. In livestock, resolving the differences between the effects of initial domestication ...
    • Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues 

      Crespo-Piazuelo, Daniel; Acloque, Hervé; González-Rodríguez, Olga; Mongellaz, Mayrone; Mercat, Marie-José; Bink, Marco C A M; Huisman, Abe E; Ramayo-Caldas, Yuliaxis; Sanchez, Juan Pablo; Ballester Devis, Maria (GigaScience, 2023-06-24) Genètica i Millora Animal
      Background In humans and livestock species, genome-wide association studies (GWAS) have been applied to study the association between variants distributed across the genome and a phenotype of interest. ...
    • Influence of dietary n-3 long-chain fatty acids on microbial diversity and composition of sows’ feces, colostrum, milk, and suckling piglets’ feces 

      Llauradó-Calero, Eudald; Climent, Eric; Chenoll, Empar; Ballester Devis, Maria; Badiola, Ignacio; Lizardo, Rosil; Torrallardona, David; Esteve-Garcia, Enric; Tous, Núria (Frontiers in Microbiology, 2022-12-05) Genètica i Millora Animal; Nutrició Animal; Sanitat Animal
      Introduction: Very little is known about the impact of n-3 long-chain fatty acids (n-3 LCFAs) on the microbiota of sows and their piglets. The aim of this study was to evaluate the effect of n-3 LCFA ...
    • Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs 

      Sebastià, Cristina; Folch, Josep M.; Ballester, Maria; Estellé, Jordi; Passols, Magí; Muñoz, María; García-Casco, Juan M.; Fernández, Ana I.; Castelló, Anna; Sánchez, Armand; Crespo-Piazuelo, Daniel (mSystems, 2023-12-14) Genètica i Millora Animal
      The gut microbiota is a key player in the host metabolism. Some bacteria are able to ferment non-digestible compounds and produce short-chain fatty acids that the host can later transform and accumulate ...
    • Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver 

      Hernández-Banqué, Carles; Jové-Juncà, Teodor; Crespo-Piazuelo, Daniel; González-Rodríguez, Olga; Ramayo-Caldas, Yuliaxis; Esteve-Codina, Anna; Mercat, Marie-José; Bink, Marco C. A. M.; Quintanilla, Raquel; Ballester, Maria (Frontiers in Immunology, 2023-09-14) Genètica i Millora Animal
      C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
    • On the holobiont ‘predictome’ of immunocompetence in pigs 

      Calle-García, Joan; Ramayo-Caldas, Yuliaxis; Zingaretti, Laura M.; Quintanilla, Raquel; Ballester Devis, Maria; Pérez-Enciso, Miguel (Genetics Selection Evolution, 2023-05-01) Genètica i Millora Animal
      Background Gut microbial composition plays an important role in numerous traits, including immune response. Integration of host genomic information with microbiome data is a natural step in the prediction ...
    • PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs 

      Zeng, Haonan; Zhang, Wenjing; Lin, Qing; Gao, Yahui; Teng, Jinyan; Xu, Zhiting; Cai, Xiaodian; Zhong, Zhanming; Wu, Jun; Liu, Yuqiang; Diao, Shuqi; Wei, Chen; Gong, Wentao; Pan, Xiangchun; Li, Zedong; Huang, Xiaoyu; Chen, Xifan; Du, Jinshi; The PigGTEx Consortium; Zhao, Fuping; Zhao, Yunxiang; Ballester, Maria; Crespo-Piazuelo, Daniel; Amills, Marcel; Clop, Alex; Karlskov-Mortensen, Peter; Fredholm, Merete; Li, Pinghua; Huang, Ruihua; Tang, Guoqing; Li, Mingzhou; Liu, Xiaohong; Chen, Yaosheng; Zhang, Qin; Li, Jiaqi; Yuan, Xiaolong; Ding, Xiangdong; Fang, Lingzhao; Zhang, Zhe (Nucleic Acids Research, 2023-11-13) Genètica i Millora Animal
      To fully unlock the potential of pigs as both agricultural species for animal-based protein food and biomedical models for human biology and disease, a comprehensive understanding of molecular and ...
    • Quantification of camelid cytokine mRNA expression in PBMCs by microfluidic qPCR technology 

      Rodon, Jordi; Te, Nigger; Ballester, Maria; Segalés, Joaquim; Vergara-Alert, Júlia; Bensaid, Albert (Developmental and Comparative Immunology, 2023-09-17) Genètica i Millora Animal; Sanitat Animal
      Camelids are economically and socially important in several parts of the world and might carry pathogens with epizootic or zoonotic potential. However, biological research in these species is limited ...