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Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(BMC, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows
(Frontiers Media, 2018-10-18)
In a previous study, we observed that circadian clock genes are differentially expressed
in the skeletal muscle of fasting and fed sows. The goal of the current work was
to investigate if these genes ...
Polymorphisms of the cryptochrome 2 and mitoguardin 2 genes are associated with the variation of lipid-related traits in Duroc pigs
(Nature Research, 2019-06-21)
The genetic factors determining the phenotypic variation of porcine fatness phenotypes are still largely
unknown. We investigated whether the polymorphism of eight genes (MIGA2, CRY2, NPAS2, CIART,
ARNTL2, ...
Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach
(Elsevier, 2019-12-06)
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we ...
Detection of homozygous genotypes for a putatively lethal recessive mutation in the porcine argininosuccinate synthase 1 (ASS1) gene
(Wiley, 2019-11-15)
The sequencing of the pig genome revealed the existence of homozygous individuals for a nonsense mutation in the argininosuccinate synthase 1 (ASS1) gene (rs81212146, c.944T>A, L315X). Paradoxically, ...
An association analysis for 14 candidate genes mapping to meat quality quantitative trait loci in a Duroc pig population reveals that the ATP1A2 genotype is highly associated with muscle electric conductivity
(Wiley, 2019-10-21)
In previous GWAS carried out in a Duroc commercial line (Lipgen population), we detected on pig chromosomes 3, 4 and 14 several QTL for gluteus medius muscle redness (GM a*), electric conductivity in ...
An association analysis between a polymorphism in the SEC24A gene and lipid traits recorded in Duroc pigs
(Taylor & Francis Open Access, 2021-10-05)
By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that ...
Modeling microRNA-driven post-transcriptional regulation using exon–intron split analysis in pigs
(Wiley, 2022-07-10)
The contribution of microRNAs (miRNAs) to mRNA post-transcriptional regulation has often been explored by the post hoc selection of downregulated genes and determining whether they harbor binding sites ...
Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
(BMC, 2017-08-10)
Background: The genetic basis of muscle fat deposition in pigs is not well known. So far, we have only identified a limited number of genes involved in the absorption, transport, storage and catabolism ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...