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Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese-making properties and milk composition in Montbéliarde cows
(BMC, 2019-07-01)
Background
Milk quality in dairy cattle is routinely assessed via analysis of mid-infrared (MIR) spectra; this approach can also be used to predict the milk’s cheese-making properties (CMP) and ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Integration of GWAS, pathway and network analyses reveals novel mechanistic insights into the synthesis of milk proteins in dairy cows
(Nature Research, 2018-01-12)
The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
Polymorphism in the ELOVL6 Gene Is Associated with a Major QTL Effect on Fatty Acid Composition in Pigs
(Public Library of Science, 2013-01-14)
Background: The ELOVL fatty acid elongase 6 (ELOVL6), the only elongase related to de novo lipogenesis, catalyzes the ratelimiting step in the elongation cycle by controlling the fatty acid balance in ...
A gene co-association network regulating gut microbial communities in a Duroc pig population
(BMC, 2021-02-21)
Background. Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic ...
About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
(BMC, 2019-06-24)
Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to
understand how gene expression is genetically regulated in a context-dependent manner. In ...
Integrating genome-wide co-association and gene expression to identify putative regulators and predictors of feed efficiency in pigs
(BMC, 2019-09-02)
Background: Feed efciency (FE) has a major impact on the economic sustainability of pig production. We used a
systems‑based approach that integrates single nucleotide polymorphism (SNP) co‑association ...