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Effect of spray-drying and ultraviolet C radiation as biosafety steps for CSFV and ASFV inactivation in porcine plasma
(Public Library of Science, 2021-04-28)
Spray-dried animal plasma (SDAP) is widely used in diets of domestic animals to improve health status and increase growth and feed efficiency. Individual steps in the SDAP manufacturing process, including ...
Identification of Single Amino Acid Changes in the Rift Valley Fever Virus Polymerase Core Domain Contributing to Virus Attenuation In Vivo
(Frontiers Media, 2022-04-28)
Rift Valley fever (RVF) is an arboviral zoonotic disease affecting many African countries with
the potential to spread to other geographical areas. RVF affects sheep, goats, cattle and
camels, causing ...
Exploring the Antiviral Potential of Natural Compounds against Influenza: A Combined Computational and Experimental Approach
(MDPI, 2024-04-30)
The influenza A virus nonstructural protein 1 (NS1), which is crucial for viral replication
and immune evasion, has been identified as a significant drug target with substantial potential to
contribute ...
Vaccination of Calves with the Mycobacterium bovis BCG Strain Induces Protection against Bovine Tuberculosis in Dairy Herds under a Natural Transmission Setting
(MDPI, 2022-04-22)
Bovine tuberculosis (bTB) is a zoonotic disease caused mainly by Mycobacterium bovis, which is associated with major economic losses for milk and meat producers. The objective of this trial was to assess ...
Immunogenicity and protection against Mycobacterium caprae challenge in goats vaccinated with BCG and revaccinated after one year
(MDPI, 2020-12-10)
Vaccination has been proposed as a supplementary tool for the control of tuberculosis in livestock. The long-term immunogenicity elicited by bacillus Calmette-Guerin (BCG) and the efficacy of revaccination ...
Senecavirus A seroprevalence and risk factors in United States pig farms
(Frontiers Media, 2022-10-20)
Senecavirus A (SVA) is a non-enveloped, single-stranded, positive-sense RNA
virus belonging to the Picornaviridae family. Senecavirus A is constantly
associated with outbreaks of vesicular disease in ...
Variations in association of nasal microbiota with virulent and non-virulent strains of Glaesserella (Haemophilus) parasuis in weaning piglets
(BMC, 2020-02-03)
Glaesserella (formerly Haemophilus) parasuis causes Glässer's disease, which results in high economic loss in the swine industry. To understand the polymicrobial interactions of G. parasuis and the nasal ...
Evolution of Swine Influenza Virus H3N2 in Vaccinated and Nonvaccinated Pigs after Previous Natural H1N1 Infection
(MDPI, 2022-09-10)
Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed
disease that can cause important economic losses to the pig industry. Currently, this virus is endemic
in farms and, ...
Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats: endobronchial inoculation vs. intranasal nebulization
(Frontiers Media, 2023-08-11)
Background: Goats are natural hosts of tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats ...
Porcine circovirus 2 (PCV2) population study in experimentally infected pigs developing PCV2-systemic disease or a subclinical infection
(Nature Research, 2020-10-20)
Porcine circovirus 2 (PCV2) is a single stranded DNA virus with one of the highest mutation rates among DNA viruses. This ability allows it to generate a cloud of mutants constantly providing new ...