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Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infection
(BMC, 2022-09-02)
Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to public health. Here, we established an ex vivo alpaca tracheal explant (ATE) model using an air-liquid interface culture ...
Modeling the impact of surveillance activities combined with physical distancing interventions on COVID-19 epidemics at a local level
(KeAi Communications, 2022-11-17)
Physical distancing and contact tracing are two key components in controlling the COVID-
19 epidemics. Understanding their interaction at local level is important for policymakers.
We propose a flexible ...
Heterologous Systemic Prime–Intranasal Boosting Using a Spore SARS-CoV-2 Vaccine Confers Mucosal Immunity and Cross-Reactive Antibodies in Mice as well as Protection in Hamsters
(MDPI, 2022-11-10)
Background: Current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are administered systemically and typically result in poor immunogenicity at the mucosa. As a result, vaccination ...
Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance
(Nature Research, 2022-12-01)
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop ...
Concordance between Antimicrobial Resistance Phenotype and Genotype of Staphylococcus pseudintermedius from Healthy Dogs
(MDPI, 2022-11-15)
Staphylococcus pseudintermedius, a common commensal canine bacterium, is the main cause
of skin infections in dogs and is a potential zoonotic pathogen. The emergence of methicillin-resistant
S. ...
Potential of Oral Nanoparticles Containing Cytokines as Intestinal Mucosal Immunostimulants in Pigs: A Pilot Study
(MDPI, 2022-04-21)
Antimicrobial resistance is a global threat that is worryingly rising in the livestock sector.
Among the proposed strategies, immunostimulant development appears an interesting approach to
increase ...
Uptake and Survival of African Swine Fever Virus in Mealworm (Tenebrio molitor) and Black Soldier Fly (Hermetia illucens) Larvae
(MDPI, 2022-12-28)
Insect production offers a sustainable source of nutrients for livestock. This comes with a risk for transmission of pathogens from the insects into the livestock sector, including viruses causing serious ...
Whole-Genome Sequencing and De Novo Assembly of 67 Staphylococcus pseudintermedius Strains Isolated from the Skin of Healthy Dogs
(American Society for Microbiology, 2022-03-02)
We have de novo assembled 67 Staphylococcus pseudintermedius genomes, with median values of 2.6 Mbp size and 99.43% completeness, 2,386 coding sequences, 19 complete rRNAs, 59 tRNAs, and 4 noncoding ...
Revisiting Porcine Circovirus Disease Diagnostic Criteria in the Current Porcine Circovirus 2 Epidemiological Context
(MDPI, 2022-03-02)
Current knowledge on porcine circovirus diseases (PCVD) caused by Porcine circovirus 2 (PCV-2) includes the subclinical infection (PCV-2-SI), systemic (PCV-2-SD) and reproductive (PCV-2-RD) diseases, ...