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High sensitivity of one-step real-time reverse transcription quantitative PCR to detect low virus titers in large mosquito pools
(BMC, 2020-09-09)
Background: Mosquitoes are the deadliest animals in the world. Their ability to carry and spread diseases to humans causes millions of deaths every year. Due to the lack of efficient vaccines, the control ...
High-Resolution Profiling of Innate Immune Responses by Porcine Dendritic Cell Subsets in vitro and in vivo
(Frontiers Media, 2020-07-07)
The present study investigated the transcriptomic response of porcine dendritic cells (DC) to innate stimulation in vitro and in vivo. The aim was to identify DC subset-specialization, suitable Toll-like ...
African swine fever vaccines: a promising work still in progress
(BMC, 2020-07-02)
African swine fever (ASF), a disease of obligatory declaration to the World Organization for Animal Health (OIE), has contributed to poverty and underdevelopment of affected areas. The presence of ASF ...
Peste des petits ruminants at the wildlife-livestock interface in the Northern Albertine Rift and Nile Basin, East Africa
(MDPI, 2020-03-07)
In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand ...
Lack of Porcine circovirus 4 Genome Detection in Pig Samples from Italy and Spain
(MDPI, 2020-05-31)
The genus Circovirus includes several species and mostly causes asymptomatic infections. Porcine circovirus 2 (PCV-2) and, with increasing evidence, Porcine circovirus 3 (PCV-3), have been associated ...
Live Attenuated African Swine Fever Viruses as Ideal Tools to Dissect the Mechanisms Involved in Cross-Protection
(MDPI, 2020-12-21)
African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan ...
Identification of a Newly Conserved SLA-II Epitope in a Structural Protein of Swine Influenza Virus
(Frontiers Media, 2020-09-16)
Despite the role of pigs as a source of new Influenza A Virus viruses (IAV) potentially capable of initiating human pandemics, immune responses to swine influenza virus (SwIV) in pigs are not fully ...
A transcriptome analysis: Various reasons of adverse pregnancy outcomes caused by acute Toxoplasma gondii Infection
(Frontiers Media, 2020-02-19)
Background: Toxoplasma gondii (T. gondii) is an obligate intracellular parasite, which can affect the pregnancy outcomes in infected females by damaging the uterus, and the intrauterine environment as ...
Antimicrobial resistance profiles and characterization of Escherichia coli strains from cases of neonatal diarrhea in Spanish pig farms
(MDPI, 2020-04-21)
Escherichia coli is considered one of the most common agents associated with neonatal diarrhea in piglets. The aim of this work was to characterize the pathogenic and antimicrobial resistance (AMR) ...
Disease-specific changes in reelin protein and mRNA in neurodegenerative diseases
(MDPI, 2020-05-19)
Reelin is an extracellular glycoprotein that modulates neuronal function and synaptic plasticity in the adult brain. Decreased levels of Reelin activity have been postulated as a key factor during ...