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dc.contributor.authorSoler, Cassandra
dc.contributor.authorGoossens, Tim
dc.contributor.authorBermejo, Alvaro
dc.contributor.authorMigura-García, Lourdes
dc.contributor.authorCusco, Anna
dc.contributor.authorFrancino, Olga
dc.contributor.authorFraile, Lorenzo
dc.contributor.otherProducció Animalca
dc.date.accessioned2018-11-20T09:07:12Z
dc.date.available2018-11-20T09:07:12Z
dc.date.issued2018-05-25
dc.identifier.citationSoler C, Goossens T, Bermejo A, Migura-García L, Cusco A, Francino O, et al. (2018) Digestive microbiota is different in pigs receiving antimicrobials or a feed additive during the nursery period. PLoS ONE 13(5): e0197353. https://doi.org/10.1371/journal.pone.0197353ca
dc.identifier.issn1932-6203ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/78
dc.description.abstractAntimicrobials have been used in a prophylactic way to decrease the incidence of digestive disorders during the piglet post-weaning period. Nowadays, it is urgent to reduce their consumption in livestock to address the problem of antimicrobial resistance. In this study, the effect of a product on piglet microbiota has been investigated as an alternative to antimicrobials. Three groups of ten post-weaning pigs were sampled at 0, 15 and 30 days one week post-weaning; the control, antibiotic and feed additive group received a standard post-weaning diet without antibiotics or additives, the same diet as the control group but with amoxicillin and colistin sulphate and the same diet as the control group but with a feed additive (Sanacore-EN, Nutriad International N.V.), respectively. The total DNA extracted from faeces was used to amplify the 16S RNA gene for massive sequencing under manufacturer’s conditions. Sequencing data was quality filtered and analyzed using QIIME software and suitable statistical methods. In general terms, age modifies significantly the microbiota of the piglets. Thus, the oldest the animal, the highest bacterial diversity observed for the control and the feed additive groups. However, this diversity was very similar in the antibiotic group throughout the trial. Interestingly, a clear increase in abundance of Bacillus and Lactobacillus spp was detected within the feed additive group versus the antibiotic and control groups. In conclusion, the feed additive group had a positive effect in the endogenous microbiota of post-weaning pigs increasing both, the diversity of bacterial families and the abundance of lactic acid bacteria during the post-weaning period.ca
dc.format.extent22ca
dc.language.isoengca
dc.publisherPublic Library of Scienceca
dc.relation.ispartofPLOS ONEca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleDigestive microbiota is different in pigs receiving antimicrobials or a feed additive during the nursery periodca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc619 - Veterinàriaca
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0197353ca
dc.contributor.groupSanitat Animalca


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