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dc.contributor.authorBovo, Samuele
dc.contributor.authorRibani, Anisa
dc.contributor.authorMuñoz, Maria
dc.contributor.authorAlves, Estefania
dc.contributor.authorAraujo, Jose P.
dc.contributor.authorBozzi, Riccardo
dc.contributor.authorČandek-Potokar, Marjeta
dc.contributor.authorCharneca, Rui
dc.contributor.authorDi Palma, Federica
dc.contributor.authorEtherington, Graham
dc.contributor.authorFernandez, Ana I.
dc.contributor.authorGarcía, Fabián
dc.contributor.authorGarcía-Casco, Juan
dc.contributor.authorKarolyi, Danijel
dc.contributor.authorGallo, Maurizio
dc.contributor.authorMargeta, Vladimir
dc.contributor.authorMartins, José Manuel
dc.contributor.authorMercat, Marie J.
dc.contributor.authorMoscatelli, Giulia
dc.contributor.authorNúñez, Yolanda
dc.contributor.authorQuintanilla, Raquel
dc.contributor.authorRadović, Čedomir
dc.contributor.authorRazmaite, Violeta
dc.contributor.authorRiquet, Juliette
dc.contributor.authorSavić, Radomir
dc.contributor.authorSchiavo, Giuseppina
dc.contributor.authorUsai, Graziano
dc.contributor.authorUtzeri, Valerio J.
dc.contributor.authorZimmer, Christoph
dc.contributor.authorOvilo, Cristina
dc.contributor.authorFontanesi, Luca
dc.contributor.otherProducció Animalca
dc.date.accessioned2020-11-06T13:24:59Z
dc.date.available2020-11-06T13:24:59Z
dc.date.issued2020-06-26
dc.identifier.citationBovo, Samuele, Anisa Ribani, Maria Muñoz, Estefania Alves, Jose P. Araujo, Riccardo Bozzi, and Marjeta Čandek-Potokar et al. 2020. "Whole-Genome Sequencing Of European Autochthonous And Commercial Pig Breeds Allows The Detection Of Signatures Of Selection For Adaptation Of Genetic Resources To Different Breeding And Production Systems". Genetics Selection Evolution 52 (1). doi:10.1186/s12711-020-00553-7.ca
dc.identifier.issn0999-193Xca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/978
dc.description.abstractBackground Natural and artificial directional selection in cosmopolitan and autochthonous pig breeds and wild boars have shaped their genomes and resulted in a reservoir of animal genetic diversity. Signatures of selection are the result of these selection events that have contributed to the adaptation of breeds to different environments and production systems. In this study, we analysed the genome variability of 19 European autochthonous pig breeds (Alentejana, Bísara, Majorcan Black, Basque, Gascon, Apulo-Calabrese, Casertana, Cinta Senese, Mora Romagnola, Nero Siciliano, Sarda, Krškopolje pig, Black Slavonian, Turopolje, Moravka, Swallow-Bellied Mangalitsa, Schwäbisch-Hällisches Schwein, Lithuanian indigenous wattle and Lithuanian White old type) from nine countries, three European commercial breeds (Italian Large White, Italian Landrace and Italian Duroc), and European wild boars, by mining whole-genome sequencing data obtained by using a DNA-pool sequencing approach. Signatures of selection were identified by using a single-breed approach with two statistics [within-breed pooled heterozygosity (HP) and fixation index (FST)] and group-based FST approaches, which compare groups of breeds defined according to external traits and use/specialization/type. Results We detected more than 22 million single nucleotide polymorphisms (SNPs) across the 23 compared populations and identified 359 chromosome regions showing signatures of selection. These regions harbour genes that are already known or new genes that are under selection and relevant for the domestication process in this species, and that affect several morphological and physiological traits (e.g. coat colours and patterns, body size, number of vertebrae and teats, ear size and conformation, reproductive traits, growth and fat deposition traits). Wild boar related signatures of selection were detected across all the genome of several autochthonous breeds, which suggests that crossbreeding (accidental or deliberate) occurred with wild boars. Conclusions Our findings provide a catalogue of genetic variants of many European pig populations and identify genome regions that can explain, at least in part, the phenotypic diversity of these genetic resources.ca
dc.format.extent19ca
dc.language.isoengca
dc.publisherBMCca
dc.relation.ispartofGenetics Selection Evolutionca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleWhole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systemsca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.relation.projectIDEC/COST/CA15112/EU/Functional Annotation of Animal Genomes-European network/FAANG-Europeca
dc.relation.projectIDEC/H2020/634476/EU/Diversity of local pig breeds and production systems for high quality traditional products and sustainable pork chains/TREASUREca
dc.subject.udc636ca
dc.identifier.doihttps://doi.org/10.1186/s12711-020-00553-7ca
dc.contributor.groupGenètica i Millora Animalca


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/