Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
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Publication date
2021-09-21ISSN
1471-4906
Abstract
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the multiplicative cooperativity between neutralizing antibodies and CD8+ T cells and propose how this might be exploited for improving vaccine-induced protective immunity.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
10
Publisher
Elsevier
Is part of
Trends in Immunology
Citation
Bocharov, Gennady, Dmitry Grebennikov, Jordi Argilaguet, and Andreas Meyerhans. 2021. "Examining The Cooperativity Mode Of Antibody And CD8+ T Cell Immune Responses For Vaccinology". Trends In Immunology 42 (10): 852-855. doi:10.1016/j.it.2021.08.003.
Grant agreement number
MICIU/Programa Estatal de generación del conocimiento y fortalecimiento científico y tecnológico del sistema I+D+I/CEX2018-000792-M/ES/ /
MICIU-FEDER/Programa Estatal de generación del conocimiento y fortalecimiento científico y tecnológico del sistema I+D+I y Programa Estatal de I+D+I orientada a los retos de la sociedad/PID2019-106323RB-I00/ES/Characterization and manipulation of control points of virus infection fates/
Program
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2831]
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/