Porcine Protein Hydrolysates (PEPTEIVA®) Promote Growth and Enhance Systemic Immunity in Gilthead Sea Bream (Sparus aurata)
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Author
Ibarz, Antoni
Firmino, Joana P.
Fernández-Alacid, Laura
Salomón, Ricardo
Vallejos-Vidal, Eva
Polo, Javier
Reyes-López, Felipe E.
Tort, Lluis
Andree, Karl B.
Publication date
2021-07-16ISSN
2076-2615
Abstract
The effects of porcine plasma protein hydrolysate (PPH) on growth, feed efficiency, and immune responses was evaluated in Sparus aurata. Fish were fed two isoproteic (48% protein), isolipidic (17% fat), and isoenergetic diets (21.7 MJ/kg) diets, one of them containing 5% PPH at the expense of fishmeal. Both diets were tested for 92 days. A significant increase in growth was observed in fish fed the PPH diet in comparison to the control group (182.2 ± 4.4 vs. 173.8 ± 4.1 g), as well as an increase in feed intake without worsening FCR values. An ex vivo assay, with splenocytes incubated with lipopolysaccharide, was conducted to evaluate the cellular immune competence of fish. Genes involved in humoral immunity (lys, IgM), pro- (tnf-α, il-1β), and anti-inflammatory (tgf-β1, il10) cytokines were upregulated in the PPH group in comparison to the control group. The inclusion of PPH in diets enhanced the antibacterial capacity of skin mucus, as the co-culture of selected bacteria (E. coli, V. anguillarum, and P. anguilliseptica) with skin mucus indicated. The present results showed that the PPH in low fishmeal diets (2%) promoted growth and feed efficiency, as well as enhancing the immune response, which indicates that this is a safe and functional ingredient for aquafeeds.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
637 - Produce of domestic (farmyard) animals and game
Pages
16
Publisher
MDPI
Is part of
Animals
Citation
Gisbert, Enric, Antoni Ibarz, Joana P. Firmino, Laura Fernández-Alacid, Ricardo Salomón, Eva Vallejos-Vidal, and Alberto Ruiz et al. 2021. "Porcine Protein Hydrolysates (PEPTEIVA®) Promote Growth And Enhance Systemic Immunity In Gilthead Sea Bream (Sparus Aurata)". Animals 11 (7): 2122. doi:10.3390/ani11072122.
Grant agreement number
MAPAMA/JACUMAR/ /ES/Estrategias nutricionales para la mejora en el rendimiento productivo: uso de piensos funcionales y dietas salud en acuicultura/DIETAplus
EC/H2020/727315/EU/Mediterranean Aquaculture Integrated Development/MedAID
MICIU/Programa Estatal de generación del conocimiento y fortalecimiento científico y tecnológico del sistema I+D+I y Programa Estatal de I+D+I orientada a los retos de la sociedad/PID2019-106878RB-I00/ES/Modulación de las propiedades del mucus de la piel por dietas funcionales y las condiciones de cultivo de dorada y trucha: regulación, control y aplicaciones en la acuicultura/
Program
Aqüicultura
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2831]
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/