Spray dried plasma as an alternative to antibiotics in piglet feeds, mode of action and biosafety
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Fecha de publicación
2016-07-23ISSN
2055-5660
Resumen
The use of growth promoting and therapeutic antibiotics in piglet feed has been a concerning subject over the last few decades because of the risk of generating antimicrobial resistance that could be transferred to humans. As a result, many products have been proposed as potential alternatives to the use of antibiotics, and among these, spray dried plasma is considered one of the most promising. However, there have been concerns about its biosafety, particularly during periods of emergence or re-emergence of swine diseases in different regions of the world, such as the recent porcine epidemic diarrhea virus outbreak in North America. The objectives of this paper are to review recent publications about the use of spray dried plasma as an alternative to antibiotics in weaned pig diets, the possible mechanisms of
action of spray dried plasma, and the existing evidence related to the biosafety of spray dried animal plasma. Particular attention is given to studies in which spray dried plasma has been directly compared to antibiotics or other alternative antimicrobial products. Several studies on the possible modes of action for spray dried plasma, such as preservation of gut barrier function or modulation of the immune response, are also reviewed. Finally, the paper focuses on the review of the existing studies on the risks of disease transmission with the use of spray dried plasma from porcine origin. Overall, spray dried plasma is a promising alternative to in-feed antimicrobials for piglets, particularly during the early stages of the post-weaning phase. Additionally, there is enough evidence to support that commercial spray dried porcine plasma is a safe product for pigs.
Tipo de documento
Artículo
Versión del documento
Versión publicada
Lengua
English
Materias (CDU)
636 - Explotación y cría de animales. Cría del ganado y de animales domésticos
Páginas
10
Publicado por
BMC
Publicado en
Porcine Health Management
Citación
Pérez-Bosque, Anna, Javier Polo, and David Torrallardona. 2016. "Spray Dried Plasma As An Alternative To Antibiotics In Piglet Feeds, Mode Of Action And Biosafety". Porcine Health Management 2 (1). doi:10.1186/s40813-016-0034-1.
Program
Nutrició Animal
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