Male germ cell proliferation and apoptosis in sexually immature meagre Argyrosomus regius (Asso, 1801) treated with recombinant follicle stimulating hormone
Visualitza/Obre
Autor/a
Zupa, Rosa
Giménez, Ignacio
Mylonas, Constantinos C.
Pousis, Chrysovalentinos
Passantino, Letizia
Cuko, Rezart
Corriero, Aldo
Data de publicació
2023-04-28ISSN
2045-2322
Resum
The meagre Argyrosomus regius (Asso, 1801) is a marine fish species that has an increasing aquaculture production in Europe. Lowering the age at maturity of hatchery-produced juveniles would support meagre aquaculture by reducing time between generations in selective breeding programs and reducing industrial costs for broodstock maintenance. The aim of this work was to assess the effects of a treatment with recombinant follicle stimulating hormone (rFsh), produced in ovarian cells of Chinese hamsters, on male germ cell proliferation and apoptosis in sexually immature meagre. The rFsh-treated fish had higher gonadosomatic index, larger seminiferous tubules, more abundant luminal spermatozoa, a lower density of anti-PCNA positive single A spermatogonia, a higher density of anti-PCNA positive spermatocysts and a lower incidence of germ cell apoptosis than control groups. The present study demonstrated the effectiveness of the produced rFsh in stimulating testis development and spermatogenesis in pre-pubertal meagre. Moreover, the rFsh treatment proved to be highly efficient in removing the apoptotic block of spermatogenesis observed in juvenile meagre, allowing spermatogonial survival and progress towards meiosis. The administration of rFsh did not stimulate spermatogonial self-renewal, a process whose control still needs to be elucidated.
Tipus de document
Article
Versió del document
Versió publicada
Llengua
Anglès
Matèries (CDU)
637 - Productes dels animals domèstics, de la caça i de la pesca
Pàgines
13
Publicat per
Springer Nature
Publicat a
Scientific Reports
Citació
Zupa, Rosa, Neil Duncan, Ignacio Giménez, Constantinos C. Mylonas, Chrysovalentinos Pousis, Letizia Passantino, Rezart Cuko, and Aldo Corriero. 2023. "Male Germ Cell Proliferation And Apoptosis In Sexually Immature Meagre Argyrosomus Regius (Asso, 1801) Treated With Recombinant Follicle Stimulating Hormone". Scientific Reports 13 (1). doi:10.1038/s41598-023-34102-1.
Número de l'acord de la subvenció
EC/H2020/862658/EU/New Technologies, Tools and Strategies for a Sustainable, Resilient and Innovative European Aquaculture/NewTechAqua
Programa
Aqüicultura
Aquest element apareix en la col·lecció o col·leccions següent(s)
- ARTICLES CIENTÍFICS [2575]
Els següents fitxers sobre la llicència estan associats a aquest element:
Excepte que s'indiqui una altra cosa, la llicència de l'ítem es descriu com http://creativecommons.org/licenses/by/4.0/