Complex Links between Natural Tuberculosis and Porcine Circovirus Type 2 Infection in Wild Boar
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Author
Díez-Delgado, Iratxe
Boadella, Mariana
Martín-Hernando, MariPaz
Barasona, José Angel
Beltrán-Beck, Beatriz
González-Barrio, David
Vicente, Joaquín
Garrido, Joseba M.
Gortazar, Christian
Publication date
2014-06-03ISSN
2314-6133
Abstract
Individuals in natural populations are exposed to a diversity of pathogens which results in coinfections. The aim of this study was to investigate the relation between natural infection with tuberculosis (TB) due to infection by bacteria of the Mycobacterium tuberculosis complex and porcine circovirus type 2 (PCV2) in free-ranging Eurasian wild boar (Sus scrofa). Apparent prevalence for TB lesions and PCV2 infection was extremely high in all age classes, including piglets (51% for TB; 85.7% for PCV2). Modeling results revealed that the relative risk of young (less than 2 years old) wild boar to test positive to PCV2 PCR was negatively associated with TB lesion presence. Also, an interaction between TB, PCV2, and body condition was evidenced: in wild boar with TB lesions probability of being PCV2 PCR positive increased with body condition, whereas this relation was negative for wild boar without TB lesions. This study provides insight into the coinfections occurring in free-ranging host populations that are naturally exposed
to several pathogens at an early age. Using TB and PCV2 as a case study, we showed that coinfection is a frequent event among natural populations that takes place early in life with complex effects on the infections and the hosts.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
9
Publisher
Hindawi
Is part of
BioMed Research International
Citation
Díez-Delgado, Iratxe, Mariana Boadella, MariPaz Martín-Hernando, José Angel Barasona, Beatriz Beltrán-Beck, David González-Barrio, and Marina Sibila et al. 2014. “Complex Links between Natural Tuberculosis and Porcine Circovirus Type 2 Infection in Wild Boar”. BioMed Research International 2014: 765715. doi:10.1155/2014/765715.
Grant agreement number
MICINN/Programa Nacional de Proyectos de Investigación Fundamental/AGL2011-30041/ES/CONTROL DE LA TUBERCULOSIS MEDIANTE VACUNACION EN JABALI. ELECCION DE UNA PAUTA VACUNAL/
EC/FP7/278976/EU/ANTIcipating the Global Onset of Novel Epidemics/ANTIGONE
Program
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2777]
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/