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Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs
(Public Library of Science, 2019-06-27)
The selection in commercial swine breeds for meat-production efficiency has been increasing among the past decades, reducing the intramuscular fat content, which has changed the sensorial and technological ...
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
(Springer Nature, 2018-08-28)
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its physiological similarities. The aim of this study was to describe the ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed
(PLoS ONE, 2018-03-09)
One of the major limitation for the application of QTL results in pig breeding and QTN identification has been the limited number of QTL effects validated in different animal material. The aim
of the ...
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
(Public Library of Science, 2017-05-04)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Transcriptional Characterization of Porcine Leptin and Leptin Receptor Genes
(Public Library of Science, 2013-06-18)
The leptin (LEP) and its receptor (LEPR) regulate food intake and energy balance through hypothalamic signaling. However, the LEP-LEPR axis seems to be more complex and its expression regulation has not ...
Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs
(American Society for Microbiology, 2023-12-14)
The gut microbiota is a key player in the host metabolism. Some bacteria are able to ferment non-digestible compounds and produce short-chain fatty acids that the host can later transform and accumulate ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...
Genome-wide linkage analysis of QTL for growth and body composition employing the PorcineSNP60 BeadChip
(BMC, 2012-05-20)
Background: The traditional strategy to map QTL is to use linkage analysis employing a limited number of markers.
These analyses report wide QTL confidence intervals, making very difficult to identify ...