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Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs
(Public Library of Science, 2019-06-27)
The selection in commercial swine breeds for meat-production efficiency has been increasing among the past decades, reducing the intramuscular fat content, which has changed the sensorial and technological ...
Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows
(Frontiers Media, 2018-10-18)
In a previous study, we observed that circadian clock genes are differentially expressed
in the skeletal muscle of fasting and fed sows. The goal of the current work was
to investigate if these genes ...
Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid composition
(Public Library of Science, 2019-08-08)
IGF2:g.3072G>A polymorphism has been described as the causal mutation of a maternally imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work was to study the ...
Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles
(BMC, 2019-03-04)
Background
Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...
Expression analysis of porcine miR-33a/b in liver, adipose tissue and muscle and its potential role in fatty acid metabolism
(Public Library of Science, 2021-01-26)
mir-33a and mir-33b are co-transcribed with the SREBF2 and SREBF1 transcription factors, respectively. The main role of SREBF1 is the regulation of genes involved in fatty acid metabolism, while SREBF2 ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
(Public Library of Science, 2017-05-04)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...