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Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats: endobronchial inoculation vs. intranasal nebulization
(Frontiers Media, 2023-08-11)
Background: Goats are natural hosts of tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats ...
Feeding Spray-Dried Porcine Plasma to Pigs Reduces African Swine Fever Virus Load in Infected Pigs and Delays Virus Transmission—Study 1
(MDPI, 2023-04-10)
The objective of this study was to evaluate the potential benefits of feeding spray-dried porcine plasma (SDPP) to pigs infected with African swine fever virus (ASFV). Two groups of twelve weaned pigs ...
Diverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens
(Taylor and Francis Group, 2023-06-12)
Clade 2.3.4.4 Eurasian lineage H5Nx highly pathogenic avian influenza virus (HPAIV) has become the globally dominant clade and caused global outbreaks since 2014. The clade 2.3.4.4 viruses have evolved ...
Porcine circovirus 3 (PCV-3) variability: Is it in the virus or in the classifcation criteria?
(BMC, 2023-02-09)
The continuous discovery of new viruses during the last decades has increased the need for new classification approaches and rules. Currently, the International Committee on Taxonomy of Viruses classifies ...
Porcine Forebrain Vacuolization Associated with Wasting in Pigs: A Novel Pathological Outcome Associated with Vitamin–Mineral Deficiency?
(MDPI, 2023-07-10)
The term wasting refers to a clinical sign used to describe a physical condition characterized
by growth retardation, usually of multifactorial origin. The objective of the present study was to
describe ...
Zoonotic diseases: Can the transmission of pathogens between animals and humans be controlled?
(Universitat de Valencia, 2023-02-23)
After being associated with more than six million deaths so far, the Covid-19 pandemic is one of the worst diseases of animal origin known to date. Other zoonotic diseases such as severe acute respiratory ...
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections
(Cell Press, 2023-02-14)
The contribution of cross-presenting XCR1+ dendritic cells (DCs) and SIRPα+ DCs in maintaining T cell function during exhaustion and immunotherapeutic interventions of chronic infections remains poorly ...
Protection provided by a commercial modified-live porcine reproductive and respiratory syndrome virus (PRRSV) 1 vaccine (PRRSV1-MLV) against a Japanese PRRSV2 field strain
(Korean Society of Veterinary Science, 2023-07-07)
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) vaccines do not provide full cross-protection, mainly due to the virus genetic variability. Despite this, vaccines based on ...
Molecular contamination of an animal facility during and after African swine fever virus infection
(Sciendo, 2023-12-19)
The molecular contamination of an animal facility was investigated during and after an infection with highly
pathogenic African swine fever virus (ASFV) among domestic pigs. The investigation evaluated ...
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
(MDPI, 2023-12-27)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and
non-S INDEL ...