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Disease-specific changes in reelin protein and mRNA in neurodegenerative diseases
(MDPI, 2020-05-19)
Reelin is an extracellular glycoprotein that modulates neuronal function and synaptic plasticity in the adult brain. Decreased levels of Reelin activity have been postulated as a key factor during ...
Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster
(Taylor & Francis Open Access, 2021-04-29)
Reinfections with SARS-CoV-2 have already been documented in humans, although its real incidence is currently unknown. Besides having a great impact on public health, this phenomenon raises the question ...
Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus
(BioMed Central, 2018-05-23)
Background
Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito ...
Exploratory field study on the effects of porcine circovirus 2 (PCV-2) sow vaccination at different physiological stages mimicking blanket vaccination
(BMC, 2021-04-26)
Background: The objective of the present study was to explore the benefits of Porcine circovirus 2 (PCV-2) blanket vaccination in a sow herd on productive parameters, PCV-2 infection and immune status ...
Revisiting Porcine Circovirus Disease Diagnostic Criteria in the Current Porcine Circovirus 2 Epidemiological Context
(MDPI, 2022-03-02)
Current knowledge on porcine circovirus diseases (PCVD) caused by Porcine circovirus 2 (PCV-2) includes the subclinical infection (PCV-2-SI), systemic (PCV-2-SD) and reproductive (PCV-2-RD) diseases, ...
Heterogeneity of Moraxella isolates found in the nasal cavities of piglets
(BMC, 2020-01-30)
Background
Previous studies have shown that the genus Moraxella is commonly present in the nasal microbiota of swine.
Results
In this study, 51 isolates of Moraxella were obtained from nasal swabs ...
TREM2 expression in the brain and biological fluids in prion diseases
(Springer, 2021-04-21)
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several neurodegenerative ...
Safety and Efficacy upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued Virus
(MDPI, 2024-01-05)
The introduction of three single nucleotide mutations into the genome of the virulent RVFV
ZH548 strain allows for the rescue of a fully attenuated virus in mice (ZH548-rA2). These mutations
are located ...
Genetic diversification patterns in swine influenza A virus (H1N2) in vaccinated and nonvaccinated animals
(Frontiers Media, 2023-09-15)
Influenza A viruses (IAVs) are characterized by having a segmented genome, low
proofreading polymerases, and a wide host range. Consequently, IAVs are
constantly evolving in nature causing a threat ...
Hotspot of Crimean-Congo Hemorrhagic Fever Virus Seropositivity in Wildlife, Northeastern Spain
(Centers for Disease Control and Prevention, 2021-08-09)
We conducted a serosurvey for Crimean-Congo hemorrhagic fever virus antibodies in various wildlife species in Catalonia, northeastern Spain. We detected high seroprevalence in southern Catalonia, close ...