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Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver
(Frontiers Media, 2023-09-14)
C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
Correlated genetic trends for production and welfare traits in a mouse population divergently selected for birth weight environmental variability
(Elsevier, 2016-05-12)
The objective of this work was to study the changes that, selecting for environmental variability of birth weight (BW), could bring to other interesting traits in livestock such as: survivability at ...
Efect of feed restriction on the environmental variability of birth weight in divergently selected lines of mice
(BMC, 2019-06-13)
Selection of mice for decreased environmental variability of birth weight has achieved higher survivability and larger litter size as a correlated response to canalized selection, which suggests higher ...
Genomic differentiation among varieties of Iberian pig
(Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 2020-02-26)
Aim of study: The objective of this study was to identify the autosomal genomic regions associated with genetic differentiation between three commercial strains of Iberian pig.
Area of study: Extremadura ...
Hippocampal neurogenesis and Arc expression are enhanced in high-fat fed prepubertal female pigs by a diet including omega-3 fatty acids and Bifidobacterium breve CECT8242
(Springer, 2023-05-06)
Obesity during childhood has become a pandemic disease, mainly caused by a diet rich in sugars and fatty acids. Among other negative effects, these diets can induce cognitive impairment and reduce ...
Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity
(Nature Research, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid composition
(Public Library of Science, 2019-08-08)
IGF2:g.3072G>A polymorphism has been described as the causal mutation of a maternally imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work was to study the ...
Admixture and breed traceability in European indigenous pig breeds and wild boar using genome-wide SNP data
(Nature Research, 2022-05-05)
Preserving diversity of indigenous pig (Sus scrofa) breeds is a key factor to (i) sustain the pork chain (both at local and global scales) including the production of high-quality branded products, (ii) ...
Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice
(Elsevier, 2018-03-19)
Objectives:Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OAspontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors. ...
Link-HD: a versatile framework to explore and integrate heterogeneous microbial communities
(Oxford University Press, 2019-11-18)
Motivation We present Link-HD, an approach to integrate multiple datasets. Link-HD is a generalization of ‘Structuration des Tableaux A Trois Indices de la Statistique–Analyse Conjointe de Tableaux’, a ...