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Polymorphism in the ELOVL6 Gene Is Associated with a Major QTL Effect on Fatty Acid Composition in Pigs
(Public Library of Science, 2013-01-14)
Background: The ELOVL fatty acid elongase 6 (ELOVL6), the only elongase related to de novo lipogenesis, catalyzes the ratelimiting step in the elongation cycle by controlling the fatty acid balance in ...
Gestational Caloric Restriction Alters Adipose Tissue Methylome and Offspring’s Metabolic Profile in a Swine Model
(MDPI, 2024-01-17)
Limited nutrient supply to the fetus results in physiologic and metabolic adaptations that have unfavorable consequences in the offspring. In a swine animal model, we aimed to study the effects of ...
Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs
(American Society for Microbiology, 2023-05-31)
Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...
Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits
(Elsevier, 2023-02-24)
In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is ...
RNA-seq based detection of differentially expressed genes in the skeletal muscle of Duroc pigs with distinct lipid profiles
(Nature Research, 2017-02-14)
We have used a RNA-seq approach to investigate differential expression in the skeletal muscle of swine
(N=52) with divergent lipid profiles i.e. HIGH (increased intramuscular fat and muscle saturated ...
Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits
(Nature Research, 2017-01-05)
Meat quality traits have an increasing importance in the pig industry because of their strong impact on
consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...
PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs
(Oxford University Press, 2023-11-13)
To fully unlock the potential of pigs as both agricultural species for animal-based protein food and biomedical models for human biology and disease, a comprehensive understanding of molecular and ...
Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles
(BMC, 2018-02-14)
Background: The identification of genes differentially expressed in the skeletal muscle of pigs displaying distinct
growth and fatness profiles might contribute to identify the genetic factors that ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...