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A meta-analysis of genetic and phenotypic diversity of European local pig breeds reveals genomic regions associated with breed differentiation for production traits
(BMC, 2023-12-07)
Background
Intense selection of modern pig breeds has resulted in genetic improvement of production traits while the performance of local pig breeds has remained lower. As local pig breeds have been ...
Integrative approach using liver and duodenum RNA-Seq data identifies candidate genes and pathways associated with feed efficiency in pigs
(Springer Nature, 2018-01-11)
This study aims identifying candidate genes and pathways associated with feed efficiency (FE) in pigs. Liver and duodenum transcriptomes of 37 gilts showing high and low residual feed intake (RFI) were ...
Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(BMC, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
On the holobiont ‘predictome’ of immunocompetence in pigs
(BMC, 2023-05-01)
Background
Gut microbial composition plays an important role in numerous traits, including immune response. Integration of host genomic information with microbiome data is a natural step in the prediction ...
Functional and association studies on the pig HMGCR gene, a cholesterol-synthesis limiting enzyme
(Cambridge University Press, 2009-10-23)
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is the rate-limiting enzyme in the biosynthesis of cholesterol. We have
studied the role of the HMGCR gene in pig lipid metabolism by means of ...
Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows
(Frontiers Media, 2018-10-18)
In a previous study, we observed that circadian clock genes are differentially expressed
in the skeletal muscle of fasting and fed sows. The goal of the current work was
to investigate if these genes ...
Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity
(Nature Research, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
Polymorphisms of the cryptochrome 2 and mitoguardin 2 genes are associated with the variation of lipid-related traits in Duroc pigs
(Nature Research, 2019-06-21)
The genetic factors determining the phenotypic variation of porcine fatness phenotypes are still largely
unknown. We investigated whether the polymorphism of eight genes (MIGA2, CRY2, NPAS2, CIART,
ARNTL2, ...
Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach
(Elsevier, 2019-12-06)
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we ...
Genetic parameters and associated genomic regions for global immunocompetence and other health-related traits in pigs
(Nature Research, 2020-10-28)
The inclusion of health-related traits, or functionally associated genetic markers, in pig breeding programs could contribute to produce more robust and disease resistant animals. The aim of the present ...