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Efficacy of a live attenuated vaccine in classical swine fever virus postnatally persistently infected pigs
(BMC, 2015-07-09)
Classical swine fever (CSF) causes major losses in pig farming, with various degrees of disease severity. Efficient live attenuated vaccines against classical swine fever virus (CSFV) are used routinely ...
Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications
(Public Library of Science, 2015-05-04)
It is well established that trans-placental transmission of classical swine fever virus (CSFV) during mid-gestation can lead to persistently infected offspring. The aim of the present study was to ...
Investigation of chronic and persistent classical swine fever infections under field conditions and their impact on vaccine efficacy
(BMC, 2019-07-15)
Background: Recent studies have hypothesized that circulation of classical swine fever virus (CSFV) variants when the immunity induced by the vaccine is not sterilizing might favour viral persistence. ...
Decrypting the Origin and Pathogenesis in Pregnant Ewes of a New Ovine Pestivirus Closely Related to Classical Swine Fever Virus
(MDPI, 2020-07-17)
This study shows the origin and the pathogenic role of a novel ovine pestivirus (OVPV) isolated in 2017 in Italy, as a pathogenic agent causing severe abortions after infection in pregnant ewes and high ...
Development of a Dendrimeric Peptide-Based Approach for the Differentiation of Animals Vaccinated with FlagT4G against Classical Swine Fever from Infected Pigs
(MDPI, 2021-10-02)
Classical swine fever virus (CSFV) causes a viral disease of high epidemiological and
economical significance that affects domestic and wild swine. Control of the disease in endemic
countries is based ...
Efficient detection of African Swine Fever Virus using minimal equipment through a LAMP PCR method
(Frontiers Media, 2023-01-27)
African swine fever virus (ASFV) currently represents the biggest threat to the porcine industry worldwide, with high economic impact and severe animal health and welfare concerns. Outbreaks have occurred ...
A Polyuridine Insertion in the 3′ Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets
(American Society for Microbiology, 2020-01-06)
Low-virulence classical swine fever virus (CSFV) strains make CSF eradication particularly difficult. Few data are available on the molecular determinants of CSFV virulence. The aim of the present study ...
Foetal Immune Response Activation and High Replication Rate during Generation of Classical Swine Fever Congenital Infection
(MDPI, 2020-04-14)
Classical swine fever virus (CSFV) induces trans-placental transmission and congenital viral persistence; however, the available information is not updated. Three groups of sows were infected at ...
Development of a new loop-mediated isothermal amplification test for the sensitive, rapid, and economic detection of different genotypes of Classical swine fever virus
(Frontiers Media, 2024-04-15)
Background: Classical swine fever virus (CSFV) remains one of the most
important pathogens in animal health. Pathogen detection relies on viral RNA
extraction followed by RT-qPCR. Novel technologies ...
The new emerging ovine pestivirus can infect pigs and confers strong protection against classical swine fever virus
(Wiley, 2021-04-25)
Several emerging pestiviruses have been reported lately, some of which have proved to cause disease. Recently, a new ovine pestivirus (OVPV), isolated from aborted lambs, with high genetic identity to ...