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The FlagT4G Vaccine Confers a Strong and Regulated Immunity and Early Virological Protection against Classical Swine Fever
(MDPI, 2022-09-02)
Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). FlagT4G ...
Protective Immunity to Listeria Monocytogenes Infection Mediated by Recombinant Listeria innocua Harboring the VGC Locus
(Public Library of Science, 2012-04-19)
In this study we propose a novel bacterial vaccine strategy where non-pathogenic bacteria are complemented with traits
desirable for the induction of protective immunity. To illustrate the proof of ...
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
(MDPI, 2023-12-27)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and
non-S INDEL ...
Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning
(Nature Research, 2021-03-17)
The aim of this study was to determine the possible impact of early socialization and an enriched neonatal environment to improve adaptation of piglets to weaning. We hypothesized that changes in the ...
A Novel E2 Glycoprotein Subunit Marker Vaccine Produced in Plant Is Able to Prevent Classical Swine Fever Virus Vertical Transmission after Double Vaccination
(MDPI, 2021-04-22)
The efficacy of a novel subunit vaccine candidate, based in the CSFV E2 glycoprotein
produced in plants to prevent classical swine fever virus (CSFV) vertical transmission, was evaluated.
A Nicotiana ...
The PHH-1V HIPRA vaccine: a new tool in the vaccination strategy against COVID-19
(Sociedad Española de Quimioterapia, 2023-06-12)
Objectives. Vaccination against SARS-CoV-2 is essential
to mitigate the personal, social and global impact of the coronavirus disease (COVID-19) as we move from a pandemic to
an endemic phase. Vaccines ...
Extrusion of Different Plants into Fibre for Peat Replacement in Growing Media: Adjustment of Parameters to Achieve Satisfactory Physical Fibre-Properties
(MDPI, 2021-06-10)
Peat is a highly contentious input in agriculture. Replacing or reducing peat by substitution with lignocellulosic biomass processed into fibre by twin-screw-extrusion could contribute to more sustainable ...
Integration of GWAS, pathway and network analyses reveals novel mechanistic insights into the synthesis of milk proteins in dairy cows
(Nature Research, 2018-01-12)
The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, ...
Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model
(MDPI, 2021-03-08)
Neurotrophins constitute a group of growth factor that exerts important functions in the nervous system of vertebrates. They act through two classes of transmembrane receptors: tyrosine-kinase receptors ...
Five genomic regions have a major impact on fat composition in Iberian pigs
(Nature Research, 2019-02-14)
The adipogenic nature of the Iberian pig defines many quality attributes of its fresh meat and dry-cured products. The distinct varieties of Iberian pig exhibit great variability in the genetic parameters ...