Browsing ARTICLES CIENTÍFICS by Author "Quintanilla, Raquel"

Now showing items 1-20 of 45

    • A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs 

      Crespo-Piazuelo, Daniel; Ramayo-Caldas, Yuliaxis; González-Rodríguez, Olga; Pascual, Mariam; Quintanilla, Raquel; Ballester, Maria (Frontiers in Immunology, 2021-11-26) Genètica i Millora Animal
      In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. ...

    • A compendium of genetic regulatory effects across pig tissues 

      Teng, Jinyan; Gao, Yahui; Yin, Hongwei; Bai, Zhonghao; Liu, Shuli; Zeng, Haonan; The PigGTEx Consortium; Bai, Lijing; Cai, Zexi; Zhao, Bingru; Li, Xiujin; Xu, Zhiting; Lin, Qing; Pan, Zhangyuan; Yang, Wenjing; Yu, Xiaoshan; Guan, Dailu; Hou, Yali; Keel, Brittney N.; Rohrer, Gary A.; Lindholm-Perry, Amanda K.; Oliver, William T.; Ballester, Maria; Crespo-Piazuelo, Daniel; Quintanilla, Raquel (Nature Genetics, 2024-01-04) Genètica i Millora Animal
      The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking genetic ...

    • A gene co-association network regulating gut microbial communities in a Duroc pig population 

      Reverter, Antonio; Ballester, Maria; Alexandre, Pamela A.; Mármol-Sánchez, Emilio; Dalmau, Antoni; Quintanilla, Raquel; Ramayo-Caldas, Yuliaxis (Microbiome, 2021-02-21) Genètica i Millora Animal
      Background. Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic ...

    • A meta-analysis of genetic and phenotypic diversity of European local pig breeds reveals genomic regions associated with breed differentiation for production traits 

      Poklukar, Klavdija; Mestre, Camille; Škrlep, Martin; Čandek-Potokar, Marjeta; Ovilo, Cristina; Fontanesi, Luca; Riquet, Juliette; Bovo, Samuele; Schiavo, Giuseppina; Ribani, Anisa; Muñoz, Maria; Gallo, Maurizio; Bozzi, Ricardo; Charneca, Rui; Quintanilla, Raquel; Kušec, Goran; Mercat, Marie-José; Zimmer, Christoph; Razmaite, Violeta; Araujo, Jose P.; Radović, Čedomir; Savić, Radomir; Karolyi, Danijel; Servin, Bertrand (Genetics Selection Evolution, 2023-12-07) Genètica i Millora Animal
      Background Intense selection of modern pig breeds has resulted in genetic improvement of production traits while the performance of local pig breeds has remained lower. As local pig breeds have been ...

    • About the existence of common determinants of gene expression in the porcine liver and skeletal muscle 

      González-Prendes, Rayner; Mármol-Sánchez, Emilio; Quintanilla, Raquel; Castelló, Anna; Zidi, Ali; Ramayo-Caldas, Yuliaxis; Figueiredo Cardoso, Tainã; Manunza, Arianna; Cánovas, Ángela; Amills, Marcel (BMC Genomics, 2019-06-24) Genètica i Millora Animal
      Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to understand how gene expression is genetically regulated in a context-dependent manner. In ...

    • Admixture and breed traceability in European indigenous pig breeds and wild boar using genome-wide SNP data 

      Dadousis, Christos; Muñoz, Maria; Óvilo, Cristina; Fabbri, Maria Chiara; Araújo, José Pedro; Bovo, Samuele; Čandek Potokar, Marjeta; Charneca, Rui; Crovetti, Alessandro; Gallo, Maurizio; García-Casco, Juan María; Karolyi, Danijel; Kušec, Goran; Martins, José Manuel; Mercat, Marie-José; Pugliese, Carolina; Quintanilla, Raquel; Radović, Čedomir; Razmaite, Violeta; Ribani, Anisa; Riquet, Juliet; Savić, Radomir; Schiavo, Giuseppina; Škrlep, Martin; Tinarelli, Silvia; Usai, Graziano; Zimmer, Christoph; Fontanesi, Luca; Bozzi, Riccardo (Scientific Reports, 2022-05-05) Genètica i Millora Animal
      Preserving diversity of indigenous pig (Sus scrofa) breeds is a key factor to (i) sustain the pork chain (both at local and global scales) including the production of high-quality branded products, (ii) ...

    • An association analysis between a polymorphism in the SEC24A gene and lipid traits recorded in Duroc pigs 

      Mármol-Sánchez, Emilio; Quintanilla, Raquel; Luigi-Sierra, María Gracia; Amills, Marcel (Italian Journal of Animal Science, 2021-10-05) Genètica i Millora Animal
      By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that ...

    • Analysing the Expression of Eight Clock Genes in Five Tissues From Fasting and Fed Sows 

      Cardoso, Tainã Figueiredo; Quintanilla, Raquel; Castelló, Anna; Mármol-Sánchez, Emilio; Ballester, Maria; Jordana, Jordi; Amills, Marcel (Frontiers in Genetics, 2018-10-18) Genètica i Millora Animal
      In a previous study, we observed that circadian clock genes are differentially expressed in the skeletal muscle of fasting and fed sows. The goal of the current work was to investigate if these genes ...

    • Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits 

      González-Prendes, Rayner; Derks, Martijn F.L.; Groenen, Martien A.M.; Quintanilla, Raquel; Amills, Marcel (Genomics, 2023-02-24) Genètica i Millora Animal
      In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is ...

    • Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply 

      Mármol-Sánchez, Emilio; Ramayo-Caldas, Yuliaxis; Quintanilla, Raquel; Cardoso, Tainã Figueiredo; González-Prendes, Rayner; Tibau, Joan; Amills, Marcel (Journal of Animal Science and Biotechnology, 2020-01-17) Genètica i Millora Animal
      Background The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...

    • Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles 

      González-Prendes, Rayner; Quintanilla, Raquel; Mármol-Sánchez, Emilio; Pena, Ramona N.; Ballester, Maria; Cardoso, Tainã Figueiredo; Manunza, Arianna; Casellas, Joaquim; Cánovas, Ángela; Díaz, Isabel; Noguera, José Luis; Castelló, Anna; Mercadé, Anna; Amills, Marcel (BMC Genomics, 2019-03-04) Genètica i Millora Animal
      Background Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...

    • Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs 

      Ramayo-Caldas, Yuliaxis; Crespo-Piazuelo, Daniel; Morata, Jordi; González-Rodríguez, Olga; Sebastià, Cristina; Castello, Anna; Dalmau, Antoni; Ramos-Onsins, Sebastian; Alexiou, Konstantinos G.; Folch, Josep M.; Quintanilla, Raquel; Ballester, Maria (Microbiology Spectrum, 2023-05-31) Benestar Animal; Genètica i Millora Animal; Genòmica i Biotecnologia
      Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...

    • Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources 

      Bovo, Samuele; Schiavo, Giuseppina; Ribani, Anisa; Utzeri, Valerio J.; Taurisano, Valeria; Ballan, Mohamad; Muñoz, Maria; Alves, Estefania; Araujo, Jose P.; Bozzi, Riccardo; Charneca, Rui; Di Palma, Federica; Djurkin Kušec, Ivona; Etherington, Graham; Fernandez, Ana I.; García, Fabián; García-Casco, Juan; Karolyi, Danijel; Gallo, Maurizio; Martins, José Manuel; Mercat, Marie-José; Núñez, Yolanda; Quintanilla, Raquel; Radović, Čedomir; Razmaite, Violeta; Riquet, Juliette; Savić, Radomir; Škrlep, Martin; Usai, Graziano; Zimmer, Christoph; Ovilo, Cristina; Fontanesi, Luca (Scientific Reports, 2021-02-09) Genètica i Millora Animal
      Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral ...

    • Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity 

      Ballester, Maria; Quintanilla, Raquel; Ortega, Francisco J.; Serrano, José C. E.; Cassanyé, Anna; Rodríguez-Palmero, Maria; Moreno-Muñoz, José A.; Portero-Otin, Manuel; Tibau, Joan (Scientific Reports, 2020-03-25) Genètica i Millora Animal
      Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...

    • Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles 

      Cardoso, Tainã Figueiredo; Quintanilla, Raquel; Castelló, Anna; González-Prendes, Rayner; Amills, Marcel; Cánovas, Ángela (BMC Genomics, 2018-02-14) Genètica i Millora Animal
      Background: The identification of genes differentially expressed in the skeletal muscle of pigs displaying distinct growth and fatness profiles might contribute to identify the genetic factors that ...

    • Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach 

      Mármol-Sánchez, Emilio; Cirera, Susanna; Quintanilla, Raquel; Pla, Albert; Amills, Marcel (Genomics, 2019-12-06) Genètica i Millora Animal
      Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we ...

    • Diversity across major and candidate genes in European local pig breeds 

      Muñoz, María; Bozzi, Riccardo; García, Fabián; Núñez, Yolanda; Geraci, Claudia; Crovetti, Alessandro; García-Casco, Juan; Alves, Estefania; Skrlep, Martin; Charneca, Rui; Martins, Jose M.; Quintanilla, Raquel; Tibau, Joan; Kusec, Goran; Djurkin-Kusec, Ivona; Mercat, Marie J.; Riquet, Juliette; Estelle, Jordi; Zimmer, Christoph; Razmaite, Violeta; Araujo, Jose P.; Radović, Čedomir; Savić, Radomir; Karolyi, Danijel; Gallo, Maurizio; Čandek-Potokar, Marjeta; Fontanesi, Luca; Fernández, Ana I.; Óvilo, Cristina (PLoS ONE, 2018-11-20) Genètica i Millora Animal
      The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...

    • Effects of breed‐production system on collagen, textural, and sensory traits of 10 European beef cattle breeds 

      Panea, Begoña; Olleta, José Luis; Sañudo, Carlos; Campo, María del Mar; Oliver, María Angels; Gispert, Marina; Serra, Xavier; Renand, Gilles; Oliván, María del Carmen; Jabet, Sylvie; García, Susana; López, Montaña; Izquierdo, Mercedes; García‐Cachán, María Dolores; Quintanilla, Raquel; Piedrafita, Jesús (Journal of Texture Studies, 2018-06-23) Genètica i Millora Animal; Qualitat i Tecnologia Alimentària
      In the current study the collagen, texture, and sensory characteristics of meat from 712 yearling males of 10 local Spanish and French beef breeds raised in their typical production systems were described. ...

    • Functional and association studies on the pig HMGCR gene, a cholesterol-synthesis limiting enzyme 

      Cánovas, A.; Quintanilla, Raquel; Gallardo, D.; Díaz, Isabel; Noguera, José Luis; Ramírez, O.; Pena, Romi (Animal, 2009-10-23) Genètica i Millora Animal; Qualitat i Tecnologia Alimentària
      The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is the rate-limiting enzyme in the biosynthesis of cholesterol. We have studied the role of the HMGCR gene in pig lipid metabolism by means of ...

    • Genetic architecture of innate and adaptive immune cells in pigs 

      Ballester Devis, Maria; Jové Juncà, Teodor; Pascual, Afra; López-Serrano, Sergi; Crespo-Piazuelo, Daniel; Hernández-Banqué, Carles; González-Rodríguez, Olga; Ramayo-Caldas, Yuliaxis; Quintanilla, Raquel (Frontiers in Immunology, 2023-02-06) Genètica i Millora Animal
      Pig industry is facing new challenges that make necessary to reorient breeding programs to produce more robust and resilient pig populations. The aim of the present work was to study the genetic determinism ...