Now showing items 1886-1905 of 2576

    • Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19 

      Varona, Jose F.; Landete, Pedro; Lopez-Martin, Jose A.; Estrada, Vicente; Paredes, Roger; Guisado-Vasco, Pablo; Fernandez de Orueta, Lucia; Torralba, Miguel; Fortun, Jesus; Vates, Roberto; Barberan, Jose; Clotet, Bonaventura; Ancochea, Julio; Carnevali, Daniel; Cabello, Noemi; Porras, Lourdes; Gijon, Paloma; Monereo, Alfonso; Abad, Daniel; Zuñiga, Sonia; Sola, Isabel; Rodon, Jordi; Vergara-Alert, Julia; Izquierdo-Useros, Nuria; Fudio, Salvador; Pontes, Maria Jose; de Rivas, Beatriz; Giron de Velasco, Patricia; Nieto, Antonio; Gomez, Javier; Aviles, Pablo; Lubomirov, Rubin; Belgrano, Alvaro; Sopesen, Belen; White, Kris M.; Rosales, Romel; Yildiz, Soner; Reuschl, Ann-Kathrin; Thorne, Lucy G.; Jolly, Clare; Towers, Greg J.; Zuliani-Alvarez, Lorena; Bouhaddou, Mehdi; Obernier, Kirsten; McGovern, Briana L.; Rodriguez, M. Luis; Enjuanes, Luis; Fernandez-Sousa, Jose M.; Krogan, Nevan J.; Jimeno, Jose M.; Garcia-Sastre, Adolfo (Life Science Alliance, 2022-01-10) Sanitat Animal
      Plitidepsin, a marine-derived cyclic-peptide, inhibits SARS-CoV-2 replication at nanomolar concentrations by targeting the host protein eukaryotic translation elongation factor 1A. Here, we show that ...
    • Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2 

      Barreiro, Antonio; Prenafeta, Antoni; Bech-Sabat, Gregori; Roca, Mercè; Perozo Mur, Eva; March, Ricard; González-González, Luis; Madrenas, Laia; Corominas, Júlia; Fernández, Alex; Moros, Alexandra; Cañete, Manuel; Molas, Merce; Pentinat-Pelegrin, Thais; Panosa, Clara; Moreno, Alberto; Puigvert Molas, Ester; Pol Vilarrassa, Eva; Palmada, Jordi; Garriga, Carme; Prat Cabañas, Teresa; Iglesias-Fernández, Javier; Vergara-Alert, Júlia; Lorca-Oró, Cristina; Roca, Núria; Fernández-Bastit, Leira; Rodon, Jordi; Pérez, Mònica; Segalés, Joaquim; Pradenas, Edwards; Marfil, Silvia; Trinité, Benjamin; Ortiz, Raquel; Clotet, Bonaventura; Blanco, Julià; Díaz Pedroza, Jorge; Ampudia Carrasco, Rosa; Rosales Salgado, Yaiza; Loubat-Casanovas, Jordina; Capdevila Larripa, Sara; Garcia Prado, Julia; Barretina, Jordi; Sisteré-Oró, Marta; Cebollada Rica, Paula; Meyerhans, Andreas; Ferrer, Laura (iScience, 2023-02-02) Sanitat Animal
      Current COVID-19 vaccines have been associated with a decline in infection rates, prevention of severe disease, and a decrease in mortality rates. However, SARSCoV-2 variants are continuously evolving, ...
    • Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates 

      Prenafeta, Antoni; Bech-Sàbat, Gregori; Moros, Alexandra; Barreiro, Antonio; Fernández, Alex; Cañete, Manuel; Roca, Mercè; González-González, Luis; Garriga, Carme; Confais, Joachim; Toussenot, Marion; Contamin, Hugues; Pizzorno, Andrés; Rosa-Calatrava, Manuel; Pradenas, Edwards; Marfil, Silvia; Blanco, Julià; Cebollada Rica, Paula; Sisteré-Oró, Marta; Meyerhans, Andreas; Lorca, Cristina; Segalés, Joaquim; Prat, Teresa; March, Ricard; Ferrer, Laura (iScience, 2023-06-28) Sanitat Animal
      SARS-CoV-2 emerged in December 2019 and quickly spread worldwide, continuously striking with an unpredictable evolution. Despite the success in vaccine production and mass vaccination programs, the ...
    • Predation by Macrolophus pygmaeus (Hemiptera: Miridae) on Acyrthosiphon pisum (Hemiptera: Aphididae): Influence of prey age/size and predator’s intraspecific interactions 

      Durán Prieto, Juliana; Trotta, Vincenzo; Fanti, Paolo; Castañé, Cristina; Battaglia, Donatella (European Journal of Entomology, 2016-01-08) Protecció Vegetal Sostenible
      Macrolophus pygmaeus (Hemiptera: Miridae) is an important predator of pests of horticultural crops and here its ability as a predator of Acyrthosiphon pisum (Hemiptera: Aphididae) is addressed for the ...
    • Predatory arthropods in apple orchards across Europe: Responses to agricultural management, adjacent habitat, landscape composition and country 

      Happe, Anne-Kathrin; Alins, Georgina; Blüthgen, Nico; Boreux, Virginie; Bosch, Jordi; García, Daniel; Hambäck, Peter A.; Klein, Alexandra-Maria; Martínez-Sastre, Rodrigo; Miñarro, Marcos; Müller, Ann-Kathrin; Porcel, Mario; Rodrigo, Anselm; Roquer-Beni, Laura; Samnegård, Ulrika; Tasin, Marco; Mody, Karsten (Agriculture, Ecosystems and Environment, 2019-01-15) Fructicultura
      Local agri-environmental schemes, including hedgerows, flowering strips, organic management, and a landscape rich in semi-natural habitat patches, are assumed to enhance the presence of beneficial ...
    • Predicted ecological niches and environmental resilience of different formulations of the biocontrol yeast Candida sake CPA-1 using the Bioscreen C 

      Carbó, A.; Torres, R.; Teixidó, N.; Usall, J.; Magan, N.; Medina, A. (BioControl, 2018-10-31) Postcollita
      Environmental resilience of biocontrol microorganisms has been a major bottleneck in the development of effective formulations. Candida sake is an effective biocontrol agent (BCA) against Penicillium ...
    • Predicted Release and Analysis of Novel ACE-I, Renin, and DPP-IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis 

      Bleakley, Stephen; Hayes, Maria; O’ Shea, Nora; Gallagher, Eimear; Lafarga, Tomas (Foods, 2017-12-04) Postcollita
      The renin-angiotensin-aldosterone system (RAAS) plays an important role in regulating hypertension by controlling vasoconstriction and intravascular fluid volume. RAAS itself is largely regulated by the ...
    • Predicting the carcass chemical composition and describing its growth in live pigs of different sexes using computed tomographys 

      Zomeño, Cristina; Gispert, Marina; Carabús, Anna; Brun, Albert; Font i Furnols, Maria (Animal, 2015-08-28) Qualitat i Tecnologia Alimentària
      The aims of this study were (1) to evaluate the ability of computed tomography (CT) to predict the chemical composition of live pigs and carcasses, (2) to compare the chemical composition of four different ...
    • Predicting the success of an invader: Niche shift versus niche conservatism 

      Sherpa, Stéphanie; Guéguen, Maya; Renaud, Julien; Blum, Michael G. B.; Gaude, Thierry; Laporte, Frédéric; Akiner, Mustafa; Alten, Bulent; Aranda, Carles; Barre‐Cardi, Hélène; Bellini, Romeo; Bengoa Paulis, Mikel; Chen, Xiao‐Guang; Eritja, Roger; Flacio, Eleonora; Foxi, Cipriano; Ishak, Intan H.; Kalan, Katja; Kasai, Shinji; Montarsi, Fabrizio; Pajović, Igor; Petrić, Dušan; Termine, Rosa; Turić, Nataša; Vazquez‐Prokopec, Gonzalo M.; Velo, Enkelejda; Vignjević, Goran; Zhou, Xiaohong; Després, Laurence (Ecology and Evolution, 2019-10-25) Sanitat Animal
      Invasive species can encounter environments different from their source populations, which may trigger rapid adaptive changes after introduction (niche shift hypothesis). To test this hypothesis, we ...
    • Prediction of fatty acid composition in intact and minced fat of European autochthonous pigs breeds by near infrared spectroscopy 

      Parrini, Silvia; Sirtori, Francesco; Čandek-Potokar, Marjeta; Charneca, Rui; Crovetti, Alessandro; Kušec, Ivona Djurkin; González Sanchez, Elena; Izquierdo Cebrian, Mercedes Maria; Garcia, Ana Haro; Karolyi, Danijel; Lebret, Benedicte; Ortiz, Alberto; Panella-Riera, Nuria; Petig, Matthias; Jesus da Costa Pires, Preciosa; Tejerina, David; Razmaite, Violeta; Aquilani, Chiara; Bozzi, Riccardo (Scientific Reports, 2023-05-15) Qualitat i Tecnologia Alimentària
      The fatty acids profile has been playing a decisive role in recent years, thanks to technological, sensory and health demands from producers and consumers. The application of NIRS technique on fat ...
    • Prediction of the total and standardized ileal digestible amino acid contents from the chemical composition of soybean meals of different origin in broilers 

      Sheikhhasan, Behzad Sadighi; Moravej, Hossein; Shivazad, Mahmoud; Ghaziani, Fateme; Esteve-Garcia, Enric; Kim, Woo Kyun (Poultry Science, 2020-07-04) Nutrició Animal
      The objective of this experiment was to determine total amino acid (TAA) content, standardized ileal digestibility (SID) of crude protein, and standardized ileal amino acid digestibility in 9 sources ...
    • Prediction of tissue composition of live dairy calves and carcasses by computed tomography 

      Font-i-Furnols, M.; Terré, M.; Brun, A.; Vidal, M.; Bach, A. (Livestock Science, 2020-12-13) Producció de Remugants; Qualitat i Tecnologia Alimentària
      Computed tomography (CT) is a non-destructive technique, based on X-rays, that has been used in several livestock species to evaluate carcass composition. The objective of this study was to construct ...
    • Predictive score and probability of CTX-like toxicity in fish samples from the official control of ciguatera in the Canary Islands 

      Sanchez-Henao, J. Andres; García-Álvarez, Natalia; Fernández, Antonio; Saavedra, Pedro; Silva Sergent, Freddy; Padilla, Daniel; Acosta-Hernández, Begoña; Martel Suárez, Manuela; Diogène, Jorge; Real, Fernando (Science of the Total Environment, 2019-03-30) Aigües Marines i Continentals
      This research identifies factors associated with the contamination by ciguatoxins (CTXs) in a population of fish and proposes a predictive score of the presence of CTX-like toxicity in amberjack samples ...
    • Presence of CTXs in moray eels and dusky groupers in the marine environment of the Canary Islandsds 

      Sanchez-Henao, Andres; García-Álvarez, Natalia; Silva Sergent, Freddy; Estévez, Pablo; Gago-Martínez, Ana; Martín, Francisco; Ramos-Sosa, María; Fernández, Antonio; Diogène, Jorge; Real, Fernando (Aquatic Toxicology, 2020-01-31) Aigües Marines i Continentals
      Local population frequently consumes moray eels and dusky groupers from the Canary Islands. These species are top predators and the interactions between them include predation but also, in some cases, ...
    • Presence of Vibrio mediterranei associated to major mortality in stabled individuals of Pinna nobilis L. 

      Prado, Patricia; Carrasco, Noelia; Catanese, Gaetano; Grau, Amalia; Cabanes, Pep; Carella, Francesca; García-March, Jose Rafael; Tena, José; Roque, Ana; Bertomeu, Edgar; Gras, Noelia; Caiola, Nuno; Furones, M. Dolors; Andree, Karl B. (Aquaculture, 2019-12-20) Aigües Marines i Continentals; Aqüicultura
      A major epizootic event attributed to Haplosporidium pinnae leading to 100% mortality of Pinna nobilis L. populations along Mediterranean coastlines started in the fall of 2016. As a result, a project ...
    • Preserving habitat quality at local and landscape scales increases wild bee diversity in intensive farming systems 

      Rollin, Orianne; Pérez-Méndez, Néstor; Bretagnolle, Vincent; Henry, Mickaël (Agriculture, Ecosystems and Environment, 2019-02-13) Cultius Extensius Sostenibles
      Biological diversity is influenced by many environmental factors, which can act either at a local scale (e.g. quality and quantity of feeding and nesting resources, habitat type) or at a landscape scale ...
    • Preslaughter feed withdrawal time and its effect on rabbit blood measures, gastrointestinal tract parameters and Longissimus lumborum glycolytic potential 

      Larivière-Lajoie, Anne-Sophie; Laforge, Pascal; Vincent, Antony T.; Binggeli, Simon; Cinq-Mars, Dany; Guay, Frédéric; Raymond, Frédéric; Dalmau, Antoni; Saucier, Linda (World Rabbit Science, 2023-12-26) Benestar Animal
      This study aimed to characterise the physiological response of rabbits to feed withdrawal without stress caused by crating and transport to the slaughterhouse. A total of 72 recently weaned Grimaud ...
    • Prevalence and lameness-associated risk factors in Alberta feedlot cattle 

      Davis-Unger, Jessica; Schwartzkopf-Genswein, Karen, S. G.; Pajor, Ed A.; Hendrick, Steve; Marti, Sonia; Dorin, Craig; Orsel, Karin (Translational Animal Science, 2019-03-13) Producció de Remugants
      Lameness in cattle is a health and welfare concern; however, limited information is available on risk factors and the relationship between lameness and common diseases like bovine respiratory disease ...
    • Prevalence of enteric pathogens in diarrheic and non-diarrheic samples from pig farms with neonatal diarrhea in the North East of Spain 

      Vidal, Anna; Martín-Valls, Gerard E.; Tello, Montse; Mateu, Enric; Martín, Marga; Darwich, Laila (Veterinary Microbiology, 2019-09-09) Sanitat Animal
      Diarrhea is one of the major causes of neonatal mortality in pigs. In the present study, 31 pig farms with outbreaks of neonatal diarrhea were investigated in Catalonia (NE Spain) from February 2017 ...
    • Prevalence of Salmonella in Free-Range Pigs: Risk Factors and Intestinal Microbiota Composition 

      Garrido, Victoria; Migura-García, Lourdes; Gaitán, Inés; Arrieta-Gisasola, Ainhoa; Martínez-Ballesteros, Ilargi; Fraile, Lorenzo; Grilló, María Jesús (Foods, 2021-06-18) Sanitat Animal
      Extensive pig systems are gaining importance as quality production systems and as the standard for sustainable rural development and animal welfare. However, the effects of natural foods on Salmonella ...